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1 January 2016 | ARTICLE
Do commonly used frailty models predict mortality, loss of autonomy and mental decline in older adults in northwestern Russia? A prospective cohort study
Frailty prevalence differs across countries depending on the models used to assess it that are based on various conceptual and operational definitions. This study aims to assess the clinical validity of three frailty models among community-dwellin...
Auteurs: Anna Turusheva, Elena Frolova, Elena Korystina, Dmitry Zelenukha, Pulodjon Tadjibaev, Natalia Gurina, E Hegendörfer, and Jean-Marie Degryse
1 January 2016 | ARTICLE
Evaluating the scripts and thresholds of general practitioners for diagnosing heart failure in elderly people
Multiple diagnostic algorithms for heart failure exist. However, it is unclear whether these algorithms are incorporated in the 'scripts' clinicians use in every day practice. Scripts are networks of organised knowledge that are acquired and accum...
Auteurs: Klaartje Decaluwe, Jean-Marie Degryse, and Bert Vaes
1 January 2016 | ARTICLE
Disease combinations associated with physical activity identified: the SMILE cohort study
In the search of predictors of inadequate physical activity, an investigation was conducted into the association between multimorbidity and physical activity (PA). So far the sum of diseases used as a measure of multimorbidity reveals an inverse a...
Auteurs: S Dörenkamp, IEPE Mesters, J Schepers, R Vos, Marjan van den Akker, J Teijink, and RA De Bie
1 January 2016 | ARTICLE
Gonorrhoea and Syphilis Epidemiology in Flemish General Practice 2009-2013: Results from a Registry-based Retrospective Cohort Study Compared with Mandatory Notification

BACKGROUND: The number of newly diagnosed gonorrhoea and syphilis cases has increased in Flanders in recent years. Our aim was to investigate, to which extent these diagnoses were registered by general practitioners (GPs), and to examine opport...

Auteurs: Christoph Schweikardt, Geert Goderis, Steven Elli, and Yves Coppieters
Auteurs: Wouter Froyman, Chiara Landolfo, Tom Bourne, BD Cock, A Testa, L Valentin, D Fischerova, V Holsbeke, D Franchi, L Savelli, E Epstein, A Czekierdowski, S Guerriero, R Fruscio, FP Leone, Ignace Vergote, Jan Verbakel, V Calster, and Dirk Timmerman
Auteurs: Sandra Steensels, Matthias Lannoo, Theo Thijs, Bert Avau, Jorien Laermans, Laurien Vancleef, Ricard Farre, Kristin Verbeke, and Inge Depoortere
1 January 2016 | ARTICLE
Pilot study to test the feasibility of a trial design and complex intervention on PRIoritising MUltimedication in Multimorbidity in general practices (PRIMUMpilot)
OBJECTIVE: To improve medication appropriateness and adherence in elderly patients with multimorbidity, we developed a complex intervention involving general practitioners (GPs) and their healthcare assistants (HCA). In accordance with the Medical...
Auteurs: Christiane Muth, Sebastian Harder, Lorenz Uhlmann, Justine Rochon, Birgit Fullerton, Corina Guethlin, Antje Erler, Martin Beyer, Marjan van den Akker, Rafael Perera, Andre Knottnerus, Jose M Valderas, Ferdinand M Gerlach, and Walter E Haefeli
1 January 2016 | ARTICLE
Dealing with chemotherapy-related symptoms at home: a qualitative study in adult patients with cancer
Given that chemotherapy treatments are done mostly in an outpatient setting, patients with cancer must deal with treatment-related symptoms mainly at home. Evidence suggests that they often feel left alone or unprepared to do so. This qualitative ...
Auteurs: Annemarie Coolbrandt, Bernadette Dierckx de Casterlé, Hans Wildiers, Bert Aertgeerts, Elisa Van der Elst, Theo van Achterberg, and Koen Milisen
Auteurs: Sanne Peters, Geraldine Clarebout, Agnes Diemers, Nicolas Delvaux, An Verburgh, Bert Aertgeerts, and Ann Roex
1 January 2016 | BOOK
Adapting Best Practice Guidelines for the Prevention, Screening and Treatment of Substance Misuse in Adolescents to the Belgian Context (ADAPTE-youth)
Alcohol and drug misuse continues to be an important problem amongst adolescents worldwide. In order for Belgian policy makers to efficiently deal with such problems, the extent of alcohol and drug misuse among young people, including environmenta...
Auteurs:
Auteurs: Leen De Coninck, Trudy Bekkering, Bouckaert, Anja Declercq, Maud Graff, and Bert Aertgeerts
1 January 2016 | ARTICLE
[What do older patients on polypharmacy know about their prescribed drugs?].
OBJECTIVE: To identify factors associated with appropriate knowledge about the indications for drugs prescribed to older patients on polypharmacy. DESIGN: Cross-sectional study. METHOD: In a primary care setting, patients aged 60 years and over wh...
Auteurs: D Bosch-Lenders, DWHA Maessen, HEJH Stoffers, JA Knottnerus, B Winkens, and M van den Akker
Auteurs: Susan M Smith, Joanne Reeve, Jane Gunn, Nathan R Hill, Martin Fortin, Catherine A O'Donnell, Marjan van den Akker, Joanne Protheroe, and Stewart W Mercer
1 January 2016 | ARTICLE
The frequency and outcome of acute dyspnoea in primary care: an observational study
Background: Little is known about the occurrence of acute dyspnoea in primary care and its underlying causes. Objectives: What are the occurrence and most frequent causes of acute dyspnoea in primary care, predictors of referral, hospitalization, ...
Auteurs: Karin von Winckelmann, Walter Renier, Matthew Thompson, and Frank Buntinx
1 January 2016 | ARTICLE
Nachtelijke onrust bij personen met dementie in woonzorgcentra: een verkennende veldstudie. (Nighttime restlessness in people with dementia in residential care: an explorative field study)
Agitatie tijdens de nacht of nachtelijke onrust is een onderschat probleem. Hoewel er weinig prevalentiecijfers bekend zijn en niet alle personen met dementie ermee te maken hebben, is het zeer belastend voor de betrokkene en voor de zorgverleners...
Auteurs: Marieke Van Vracem, Nele Spruytte, Anja Declercq, and Chantal Van Audenhove
1 January 2016 | ARTICLE
Tailored expectant management in couples with unexplained infertility does not influence their experiences with the quality of fertility care
STUDY QUESTION: Do couples who were eligible for tailored expectant management (TEM) and did not start treatment within 6 months after the fertility work-up, have different experiences with the quality of care than couples that were also eligible ...
Auteurs: FAM Kersten, RPGM Hermens, DDM Braat, E Tepe, A Sluijmer, WK Kuchenbecker, N Van den Boogaard, BWJ Mol, M Goddijn, and WLDM Nelen
1 January 2016 | ARTICLE
Health effects of training laypeople to deliver emergency care in underserviced populations: a systematic review protocol
INTRODUCTION: The Disease Control Priorities Project recommends emergency care training for laypersons in low-resource settings, but evidence for these interventions has not yet been systematically reviewed. This review will identify the individua...
Auteurs: Aaron M Orkin, Jeffrey D Curran, Melanie K Fortune, Allison McArthur, Emma J Mew, Stephen D Ritchie, Stijn Van de Velde, and David VanderBurgh
1 January 2016 | ARTICLE
Factors associated with appropriate knowledge of the indications for prescribed drugs among community-dwelling older patients with polypharmacy
BACKGROUND: polypharmacy contributes to patients' non-adherence with physicians' prescriptions. Patients' knowledge about the indications for their medicines is one of the factors influencing adherence. OBJECTIVE: to identify factors associated wi...
Auteurs: Donna Bosch-Lenders, Denny WHA Maessen, Henri EJH Jelle Stoffers, J Andre Knottnerus, Bjorn Winkens, and Marjan van den Akker
Auteurs: Christiane Muth, Marjan van den Akker, and Paul P Glasziou
1 January 2016 | ARTICLE
Quantitative genome-wide methylation analysis of high-grade non-muscle invasive bladder cancer
High-grade non-muscle invasive bladder cancer (HG-NMIBC) is a clinically unpredictable disease with greater risks of recurrence and progression relative to their low-intermediate-grade counterparts. The molecular events, including those affecting ...
Auteurs: Mark O Kitchen, Richard T Bryan, Richard D Emes, John R Glossop, Christopher Luscombe, KK Cheng, Maurice P Zeegers, Nicholas D James, Adam J Devall, Charles A Mein, Lyndon Gommersall, Anthony A Fryer, and William E Farrell
1 January 2016 | ARTICLE
Association between Blood Omega-3 Index and Cognition in Typically Developing Dutch Adolescents
The impact of omega-3 long-chain polyunsaturated fatty acids (LCPUFAs) on cognition is heavily debated. In the current study, the possible association between omega-3 LCPUFAs in blood and cognitive performance of 266 typically developing adolescen...
Auteurs: Inge SM van der Wurff, Clemens von Schacky, Kjetil Berge, Maurice P Zeegers, Paul A Kirschner, and Renate HM de Groot
1 January 2016 | ARTICLE
Geographical Variation in Antipsychotic Drug Use in Elderly Patients with Dementia: A Nationwide Study
BACKGROUND: Use of antipsychotics in elderly patients with dementia has decreased in the past decade due to safety regulations; however use is still high. Geographical variation may indicate discrepancies in clinical practice and lack of adherence...
Auteurs: Johanne Kobstrup Zakarias, Christina Jensen-Dahm, Ane Norgaard, Lea Stevnsborg, Christiane Gasse, Bodil Gramkow Andersen, Soren Jakobsen, Frans Boch Waldorff, Torben Moos, and Gunhild Waldemar
1 January 2016 | ARTICLE
The role of diseases, risk factors and symptoms in the definition of multimorbidity - a systematic review
UNLABELLED: Objective is to explore how multimorbidity is defined in the scientific literature, with a focus on the roles of diseases, risk factors, and symptoms in the definitions. DESIGN: Systematic review. METHODS: MEDLINE (PubMed), Embase, and...
Auteurs: Tora Grauers Willadsen, Anna Bebe, Rasmus Koster-Rasmussen, Dorte Ejg Jarbol, Ann Dorrit Guassora, Frans Boch Waldorff, Susanne Reventlow, and Niels de Fine Olivarius
1 January 2016 | BOOK CHAPTER
A process evaluation of ADAPTE-youth: an alternative to de novo evidence-based practice guideline development
Currently, guidelines for the prevention, screening, assessment and treatment for adolescents who misuse alcohol or drugs are lacking in Belgium. For this reason, the ADAPTE-youth project was performed aiming to develop guidelines for the Belgian ...
Auteurs: Trudy Bekkering, Elke Emmers, and Karin Hannes
1 January 2016 | ARTICLE
Prognostic value of handgrip strength in people aged 60 years and older: A systematic review and meta-analysis
AIM: The aim of the present study was to systematically review the literature on the predictive value of handgrip strength as a marker for vulnerability. Furthermore, we aimed to update a recent systematic review on the association between handgri...
Auteurs: JM Rijk, PRKM Roos, L Deckx, Marjan van den Akker, and Frank Buntinx
1 January 2016 | OTHER
Hoe handelt de Vlaamse huisarts bij dementie?
OBJECTIVE: In 2015, research showed that there is still a lot of discussion concerning the approach of dementia among general practitioners (GPs) in the region Zuiderkempen. The following study examines how GPs in Flanders deal with dementia in te...
Auteurs: Deplhine Despriet, Elien Van de Putte, Herlinde Van Eecke, Jan Steyaert, Birgitte Schoenmakers, and Jan De Lepeleire
Auteurs: Tessa Vansant, N Dessers, K Lemmens, S Geens, K Bollen, G Cloosen, Erika Vanhauwaert, Kathleen Claes, and Gijs Van Pottelbergh
1 January 2016 | ARTICLE
Mortality, hospitalisation, institutionalisation in community-dwelling oldest old: The impact of medication
High drug use and associated adverse outcomes are common in older adults. This study investigates association of medication use with mortality, hospitalisation, and institutionalisation in a cohort of community-dwelling oldest old (aged 80 and over).
Auteurs: Maarten Wauters, Monique Elseviers, Bert Vaes, Jan Degryse, Robert Vander Stichele, Thierry Christiaens, and Majda Azermai