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5 July 2019 | ARTICLE
Health related quality of life in multimorbidity: a primary-care based study from Odisha, India
BACKGROUND: Multimorbidity, the coexistence of two or more chronic conditions is increasingly prevalent in primary care populations. Despite reports on its adverse impact on health outcomes, functioning and well-being, it's association with qualit...
Auteurs: Sanghamitra Pati, Subhashisa Swain, J Andre Knottnerus, Job FM Metsemakers en Marjan van den Akker
4 July 2019 | ARTICLE
Defining quality indicators for heart failure in general practice
Background: Quality indicators (QIs) are used to measure and evaluate quality of care. However, QIs to evaluate care for HF patients in general practice in Belgium are lacking. Therefore, this study aimed to determine which QIs, rooted in the elec...
Auteurs: Marie Smets, Miek Smeets, Steve Van den Bulck, Stefan Janssens, Bert Aertgeerts en Bert Vaes
1 July 2019 | ARTICLE
The Clinical Utility of Point-of-Care Tests for Influenza in Ambulatory Care: A Systematic Review and Meta-analysis
BACKGROUND: Point-of-care tests (POCTs) for influenza are diagnostically superior to clinical diagnosis, but their impact on patient outcomes is unclear. METHODS: A systematic review of influenza POCTs versus usual care in ambulatory care settings...
Auteurs: Joseph Jonathan Lee, Jan Y Verbakel, Clare Rosemary Goyder, Thanusha Ananthakumar, Pui San Tan, Phillip James Turner, Gail Hayward en Ann Van den Bruel
1 July 2019 | ARTICLE
C-reactive protein and neutrophil count laboratory test requests from primary care: what is the demand and would substitution by point-of-care technology be viable?
UNLABELLED: AIMS : C-reactive protein (CRP) and neutrophil count (NC) are important diagnostic indicators of inflammation. Point-of-care (POC) technologies for these markers are available but rarely used in community settings in the UK. To inform ...
Auteurs: Jose M Ordonez-Mena, Thomas R Fanshawe, David McCartney, Brian Shine, Ann Van den Bruel, Daniel Lasserson en Gail Hayward
1 July 2019 | ARTICLE
Exploring intergenerational differences in burnout and how they relate to work engagement, norms, and values: a mixed-methods study.
BACKGROUND: Burnout has been on the rise in recent years. Is this increasing prevalence due to changing working circumstances, or also to a changing societal context? AIM: The aim of the study was to explore intergenerational differences in burnou...
Auteurs: Carolien De Maeyer en Birgitte Schoenmakers
Auteurs: Caroline Robertson, Marjan van den Akker, Mieke Maaskant en Nehalennia van Hanegem
28 June 2019 | ARTICLE
General practitioners' perceptions about their role in current and future heart failure care: an exploratory qualitative study
BACKGROUND: A comprehensive disease management programme (DMP) with a central role for general practitioners (GPs) is needed to improve heart failure (HF) care. However, previous research has shown that GPs have mixed experiences with multidiscipl...
Auteurs: Miek Smeets, Sofia Zervas, Hanne Leben, Mieke Vermandere, Stefan Janssens, Wilfried Mullens, Bert Aertgeerts en Bert Vaes
21 June 2019 | ARTICLE
Asymptomatic bacteriuria in older adults: the most fragile women are prone to long-term colonization
BACKGROUND: The diagnosis of urinary tract infections (UTIs) in institutionalized older adults is often based on vague symptoms and a positive culture. The high prevalence of asymptomatic bacteriuria (ABU), which cannot be easily discriminated fro...
Auteurs: Michael Biggel, Stefan Heytens, Katrien Latour, Robin Bruyndonckx, Herman Goossens en Pieter Moons
Auteurs: Filip Cools en Alexander Lemmens
1 June 2019 | ARTICLE
The successful uptake and sustainability of rapid infectious disease and antimicrobial resistance point-of-care testing requires a complex "mix-and-match' implementation package
The emergence and spread of antimicrobial resistance is one of the major global issues currently threatening the health and wealth of nations, with effective guidelines and intervention strategies urgently required. Such guidelines and interventio...
Auteurs: John P Hays, Konstantinos Mitsakakis, Saturnino Luz, Alex van Belkum, Karsten Becker, Ann van den Bruel, Stephan Harbarth, John H Rex, Gunnar Skov Simonsen, Guido Werner, Valentina Di Gregori, Gerd Luedke, Tjeerd van Staa, Jacob Moran-Gilad en Till T Bachmann
1 June 2019 | ARTICLE
Exploring the association between whole blood Omega-3 Index, DHA, EPA, DHA, AA and n-6 DPA, and depression and self-esteem in adolescents of lower general secondary education
PURPOSE: Depression is common in adolescents and long-chain polyunsaturated fatty acids (LCPUFA) are suggested to be associated with depression. However, research in adolescents is limited. Furthermore, self-esteem has never been studied in relati...
Auteurs: ISM van der Wurff, C von Schacky, T Bergeland, R Leontjevas, MP Zeegers, PA Kirschner en RHM de Groot
1 June 2019 | ARTICLE
Impact of point-of-care C reactive protein in ambulatory care: a systematic review and meta-analysis
OBJECTIVE: The aim of this review was to collate all available evidence on the impact of point-of-care C reactive protein (CRP) testing on patient-relevant outcomes in children and adults in ambulatory care. DESIGN: This was a systematic review to...
Auteurs: Jan Y Verbakel, Joseph J Lee, Clare Goyder, Pui San Tan, Thanusha Ananthakumar, Philip J Turner, Gail Hayward en Ann Van den Bruel
Auteurs: S Bobdiwala, S Saso, JY Verbakel, M Al-Memar, B Van Calster, D Timmerman en T Bourne
1 June 2019 | ARTICLE
A systematic review shows no performance benefit of machine learning over logistic regression for clinical prediction models
OBJECTIVES: The objective of this study was to compare performance of logistic regression (LR) with machine learning (ML) for clinical prediction modeling in the literature. STUDY DESIGN AND SETTING: We conducted a Medline literature search (1/201...
Auteurs: Evangelia Christodoulou, Jie Ma, Gary S Collins, Ewout W Steyerberg, Jan Y Verbakel en Ben Van Calster
1 June 2019 | ARTICLE
Critical reflections on the blind sides of frailty in later life
Since the 1970's, frailty emerged as a major theme and has become one of the most researched topics in aging studies. However, throughout the years, the concept 'frailty' became susceptible to different interpretations and has been approached by d...
Auteurs: Liesbeth De Donder, An-Sofie Smetcoren, Jos MGA Schols, Anne van der Vorst, Eva Dierckx, L De Donder, D Lambotte, B Fret, D Duppen, M Kardol, D Verte, L Hoeyberghs, N De Witte, E De Roeck, S Engelborghs, PP Dedeyn, MCJ Van der Elst, J De Lepeleire, B Schoenmakers, GAR Zijlstra en GIJM Kempen
1 June 2019 | ARTICLE
Focusing on positive outcomes in frailty research: development of a short well-being instrument for older adults (SWIO)
UNLABELLED: ABSTRACTObjective:Studies of frailty have tended to focus on adverse outcomes. This study aims to develop a short instrument that identifies a positive outcome, namely, the level of well-being in older adults at risk of frailty. METHOD...
Auteurs: Daan Duppen, Gina Rossi, Eva Dierckx, Lieve Hoeyberghs, Liesbeth De Donder, A-S Smetcoren, S Dury, N De Witte, D Lambotte, B Fret, D Duppen, M Kardol, D Verte, E De Roeck, S Engelborghs, PP Dedeyn, MCJ Van der Elst, J De Lepeleire, B Schoenmakers, A van der Vorst, GAR Zijlstra, GIJM Kempen en JMGA Schols
1 June 2019 | ARTICLE
Think-aloud study about the diagnosis of chronic heart failure in Belgian general practice
OBJECTIVES: Diagnosing chronic heart failure (CHF) in general practice is challenging. Our aim was to investigate how general practitioners (GPs) diagnose CHF in real-world patients. DESIGN: Think-aloud study. METHODS: Fourteen GPs were asked to r...
Auteurs: Miek Smeets, Pieter De Witte, Sanne Peters, Bert Aertgeerts, Stefan Janssens en Bert Vaes
Auteurs: Sophie Opsomer, Peter Pype, Emelien Lauwerier en Jan De Lepeleire
14 May 2019 | ARTICLE
Thyroid hormones treatment for subclinical hypothyroidism: a clinical practice guideline
CLINICAL QUESTION: What are the benefits and harms of thyroid hormones for adults with subclinical hypothyroidism (SCH)? This guideline was triggered by a recent systematic review of randomised controlled trials, which could alter practice. CURREN...
Auteurs: GE Bekkering, T Agoritsas, L Lytvyn, AF Heen, M Feller, E Moutzouri, H Abdulazeem, B Aertgeerts, D Beecher, JP Brito, PD Farhoumand, N Singh Ospina, N Rodondi, M van Driel, E Wallace, M Snel, PM Okwen, R Siemieniuk, PO Vandvik, T Kuijpers en M Vermandere
3 May 2019 | ARTICLE
P300, grey matter volume and individual characteristics correlates in healthy elderly
We investigated whether P300-ERP and cognitive test performance differ for age, sex, and education in two groups of healthy elderly, and verified whether any correlations exist between P300 amplitude and latency and gray matter volume using whole ...
Auteurs: Valentina Pergher, Jos Tournoy, birgitte Schoenmakers en Marc Van Hulle
2 May 2019 | OTHER
[Inside my mind, outside my body]: Towards understanding the entangled human experience of adherence to ART using a biopsychosocial-material perspective in health care for HIV positive young people in South Africa – A p[ART]icipatory co-creative approach.
In the medical sciences, the primary objective has always been to provide quality health care to patients to ensure their health and wellbeing. Traditionally, medical practice has focused on physical ailments and measurable symptoms of illness and...
Auteurs: Lynn Hendricks, karin Hannes, Taryn Young en Cathy Mathei
Auteurs: HC Sox, M Aerts, J Haasenriter, G Minalu, S Bösner, F Buntinx, B Burnand, L Herzig, JA Knottnerus, S Nilsson, W Renier, CH Sox en N Donner-Banzhoff
1 May 2019 | ARTICLE
A better understanding of the concept “a good death”: How do healthcare providers define a good death?
Title: To a better understanding of the concept of “a good death”: How do patients, close relatives and healthcare providers define a good death and which affecting factors are important? Introduction: The goal of palliative care is to improve the...
Auteurs: L Vanderveken, Birgitte Schoenmakers en Jan De Lepeleire
1 May 2019 | ARTICLE
Predictors of Adverse Outcomes in Uncomplicated Lower Respiratory Tract Infections
PURPOSE: Presentation with acute lower respiratory tract infection (LRTI) in primary care is common. The aim of this study was to help clinicians treat patients presenting with LRTI in primary care by identifying those at risk of serious adverse o...
Auteurs: Michael Moore, Beth Stuart, Mark Lown, Ann Van den Bruel, Sue Smith, Kyle Knox, Matthew J Thompson en Paul Little
1 May 2019 | ARTICLE
Modeling the Complex Exposure History of Smoking in Predicting Bladder Cancer A Pooled Analysis of 15 Case-Control Studies
BACKGROUND: Few studies have modeled smoking histories by combining smoking intensity and duration to show what profile of smoking behavior is associated with highest risk of bladder cancer. This study aims to provide insight into the association ...
Auteurs: Frits HM van Osch, Jelle Vlaanderen, Sylvia HJ Jochems, Cristina Bosetti, Jeri Polesel, Stefano Porru, Angela Carta, Klaus Golka, Xuejuan Jiang, Mariana C Stern, Wei-De Zhong, Eliane Kellen, Hermann Pohlabeln, Li Tang, James Marshall, Gunnar Steineck, Margaret R Karagas, Kenneth C Johnson, Zuo-Feng Zhang, Jack A Taylor, Carlo La Vecchia, Richard T Bryan, Frederik J van Schooten, Anke Wesselius en Maurice R Zeegers
12 April 2019 | ARTICLE
Supporting Students With Electronic Health Record-Embedded Learning Aids: A Mixed-Methods Study.
BACKGROUND: Students often perceive workplace-based learning as disconnected from what they learn in medical school. Interventions that deal with this issue regularly involve feedback and/or learning aids. Feedback has frequently been encouraged i...
Auteurs: Sanne Peters, Geraldine Clarebout, Bert Aertgeerts, Jimmie Leppink en Ann Roex
3 April 2019 | ARTICLE
Meaning in Life for Socially Frail Older Adults
Being connected with others is fundamental for the experience of a meaningful life. Unfortunately, several older adults have poor networks/social support. The present study focuses on the experience of meaning in life as well as the loss of meanin...
Auteurs: Daan Duppen, Anja Machielse, Dominique Verte Rn, Sarah Dury, Liesbeth De Donder en D-Scope Consortium