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1 January 2011 | ARTICLE
The Danish Alzheimer Intervention Study: Rationale, Study Design and Baseline Characteristics of the Cohort
BACKGROUND: There is a lack of appropriately designed trials investigating the efficacy of psychosocial interventions for patients with mild dementia and their family caregivers. This paper reports the rationale and design of the Danish Alzheimer ...
Auteurs: G Waldemar, FB Waldorff, DV Buss, A Eckermann, N Keiding, S Rishoj, V Siersma, J Sorensen, LV Sorensen en A Vogel
1 January 2011 | ARTICLE
Selenium for preventing cancer
BACKGROUND: Selenium is a trace element essential to humans. Higher selenium exposure and selenium supplements have been suggested to protect against several types of cancers. OBJECTIVES: Two research questions were addressed in this review: What ...
Auteurs: Gabriele Dennert, Marcel Zwahlen, Maree Brinkman, Marco Vinceti, Maurice PA Zeegers en Markus Horneber
1 January 2011 | BOOK
Dementie: zakboekje voor de professionele zorgverstrekker
Dit zakboekje wil een wegwijzer zijn in de dagelijkse professionele voor patiënten met dementie en hun familie en mantelzorgers. Vertrekkende vanuit de initiële ziektediagnostiek tot de fase van het levenseinde geeft dit boekje een helder, wetensc...
Auteurs: Birgitte Schoenmakers en Jan De Lepeleire
1 January 2011 | ARTICLE
Exploring unplanned ICU admissions: a systematic review.
BACKGROUND: Adverse events are unintended patient injuries or complications that arise from healthcare management resulting in death, disability or prolonged hospital stay. Adverse events that require critical care are a considerable financial bur...
Auteurs: Annemie Vlayen, Sandra Verelst, Geertruida E Bekkering, Ward Schrooten, Johan Hellings en Nerée Claes
1 January 2011 | TEXT RESOURCE
De ervaringen van thuisverpleegkundigen bij het toepassen van vrijheidsbeperkende maatregelen: een kwalitatieve studie
SAMENVATTING ‘De ervaringen van thuisverpleegkundigen bij het toepassen van vrijheidsbeperkende maatregelen: een kwalitatieve studie’ Probleemstelling Op basis van de huidige evoluties wordt verwacht dat thuisverpleegkundigen in toenemende mate...
Auteurs: Kristien Scheepmans, Bernadette Dierckx de Casterlé, Louis Paquay, Hendrik Van Gansbeke en Koen Milisen
1 January 2011 | ARTICLE
Parenteral versus Oral Administration of Systemic Antimicrobials in European Nursing Homes A Point-Prevalence Survey
BACKGROUND: Residents in long-term care facilities are predisposed to healthcare-associated infections that are likely caused by antimicrobial-resistant micro-organisms. Long-term care facilities are increasingly able to offer parenteral antimicro...
Auteurs: Elisabeth Broex, Boudewijn Catry, Katrien Latour, Karl Mertens, Vanessa Vankerckhoven, Arno Muller, Rudi Stroobants, Peter Zarb, Herman Goossens en Beatrice Jans
Auteurs: Lotte Jew van Dijk, Willianne Ldm Nelen, Thomas D'Hooghe, Gerard Aj Dunselman, Rosella Pmg Hermens, Christina Bergh, Karl G Nygren, Arnold Hm Simons, Petra de Sutter, Catherine Marshall, Jako S Burgers en Jan Am Kremer
Auteurs: Sven Seys, Wim Adriaensen, Ellen Dilissen, marcin grabowski, ann decraene, Jeroen Vanoirbeek, Jan Ceuppens, Lieven Dupont en Dominique Bullens
1 January 2011 | ARTICLE
Systemic Hydrocortisone To Prevent Bronchopulmonary Dysplasia in preterm infants (the SToP-BPD study); a multicenter randomized placebo controlled trial
Randomized controlled trials have shown that treatment of chronically ventilated preterm infants after the first week of life with dexamethasone reduces the incidence of the combined outcome death or bronchopulmonary dysplasia (BPD). However, ther...
Auteurs: Wes Onland, Martin Offringa, Filip Cools, Anne P De Jaegere, Karin Rademaker, Henry Blom, Eric Cavatorta, Anne Debeer, Peter H Dijk, Arno F van Heijst, Boris W Kramer, Andre A Kroon, Thilo Mohns, Henrica L van Straaten, Arjan B te Pas, Claire Theyskens, Mirjam M van Weissenbruch en Anton H van Kaam
1 January 2011 | ARTICLE
Prevalence of impaired renal function in the elderly in the St. Petersburg District: results of the Crystal study
Chronic kidney disease (CKD) has a high prevalence in the elderly. It has been recognized as an independent cardiovascular risk factor and detecting CKD is also important to ensure the appropriate dose of medication and to prevent further damage b...
Auteurs: Gijs Van Pottelbergh, C Van Pottelbergh, Gurina Natalia, N Gurina, Jean-Marie Degryse, frolova elena en E Frolova
1 January 2011 | ARTICLE
The protective effect of ophthalmic viscoelastic devices on endothelial cell loss during cataract surgery: a meta-analysis using mixed treatment comparisons
BACKGROUND/AIMS: To compare ophthalmic viscoelastic devices (OVDs) in protecting the cornea from endothelial cell loss during cataract surgery. METHODS: A systematic review yielded 21 randomised controlled trials including 1769 patients. OVDs were...
Auteurs: Ann Van den Bruel, Jeannine Gailly, Stephan Devriese, Nicky J Welton, Alex J Shortt en France Vrijens
Auteurs: Geert Goderis
Auteurs: M Thompson, A Van den Bruel, Jan Verbakel, M Lakhanpaul, T Haj-Hassan, R Srevens, F Moll, Frank Buntinx, M Berger, Bert Aertgeerts, R Oostenbrink en D Mant
9 December 2010 | DISSERTATION
The proof of (un)certainty: diagnostic research on 'chest pain' in a GP setting
Over the last 20 years, a substantial change in the epidemiology of acute myocardial syndrome (ACS) has occurred. Non-ST-segment elevation myocardial infarction (NSTEMI) now constitutes the majority of AMIs and the 30-days fatality rate of hospita...
Auteurs: Rudi Bruyninckx
Auteurs: RP Ottenheijm, MJ Jansen, JB Staal, A van den Bruel, RE Weijers, RA de Bie en G-J Dinant
1 December 2010 | ARTICLE
Increased attendance rate: BMI matters, lifestyles don't. Results from the Dutch SMILE study
INTRODUCTION: a small group of frequent attenders is responsible for a disproportional large percentage of all daytime consultations in general practice. High attendance rates are related to demographic and psychological characteristics. Differenc...
Auteurs: Ben van Steenkiste, Mieke F Knevel, Marjan van den Akker en Job FM Metsemakers
1 December 2010 | ARTICLE
Excess of mortality in patients with chest pain peaks in the first three days period after the incident and normalizes after one month
Background. Patients presenting with chest pain have a 5% chance of experiencing a coronary event. These patients are at risk of mortality and should be recognized and referred to secondary care. Aim. To determine the relationship between referr...
Auteurs: Rudi Bruyninckx, Ann Van den Bruel, Frank Buntinx, Viviane Van Casteren en Bert Aertgeerts
1 December 2010 | ARTICLE
Degree of solidarity with lifestyle and old age among citizens in the Netherlands: cross-sectional results from the longitudinal SMILE study
BACKGROUND AND AIM: With the increasing interest in lifestyle, health and consequences of unhealthy lifestyles for the healthcare system, a new kind of solidarity is gaining importance: lifestyle solidarity. While it might not seem fair to let oth...
Auteurs: Linda HA Bonnie, Marjan van den Akker, Ben van Steenkiste en Rein Vos
1 December 2010 | ARTICLE
The impact of a nurse-led care programme on events and physical and psychosocial parameters in patients with heart failure with preserved ejection fraction: a randomized clinical trial in primary care in Russia
BACKGROUND: Disease management programmes (DMPs) improve quality of care for patients with heart failure (HF). However, only a limited number of trials have studied the efficacy of such programmes for patients with heart failure with preserved eje...
Auteurs: A Andryukhin, E Frolova, Bert Vaes en Jean-Marie Degryse
1 December 2010 | ARTICLE
A derivate of the antibiotic doxorubicin is a selective inhibitor of dengue and yellow fever virus replication in vitro
A doxorubicin derivate, SA-17, that carries a squaric acid amide ester moiety at the carbohydrate (α-l-daunosaminyl) group was identified as a selective inhibitor of in vitro dengue virus (DENV) serotype 2 replication (50% effective concentration ...
Auteurs: Suzanne SJ Kaptein, Tine De Burghgraeve, Mathy Froeyen, Boris Pastorino, Marijke Alen, Juan A Mondotte, Piet Herdewijn, Michael Jacobs, Xavier de Lamballerie, Dominique Schols, Andrea V Gamarnik, Ferenc Sztaricskai en Johan Neyts
Auteurs: Jan Verbakel, Johan Lisaerde en Bart Van den Eynden
26 November 2010 | ARTICLE
Medicinal use of potato-derived products: conclusions of a rapid review versus full systematic review
Vlachojannis et al reported a systematic review on the medicinal use of potato-derived products. The authors identified five trials for inclusion in the review, including one study on the treatment of burns. Based on this RCT the review authors co...
Auteurs: S Van de Velde, Emmy De Buck, T Dieltjens en Bert Aertgeerts
Auteurs: Marijke Alen, Tine De Burghgraeve, Suzanne Kaptein, Jan Balzarini, Johan Neyts en Dominique Schols
Auteurs: R Novakovic, M Gurinovic, GE Bekkering, D Ristic Medic, A Kadvan, J Ngo-de la Cruz, B Roman, L Serra-Majem, M Golsorkhi, M Warthon-Medina, Christophe Matthys en LCPGM De Groot
1 November 2010 | ARTICLE
Coronary artery calcification: a strong predictor of cardiovascular events in renal transplant recipients
BACKGROUND: Coronary artery calcification (CAC) independently predicts cardiovascular events (CVE) in the general population. Whether this applies to renal transplant recipients (RTR) is unknown. This prospective study assessed the prognostic impa...
Auteurs: Pauline TH Nguyen, Severine Henrard, Emmanuel Coche, Eric Goffin, Olivier Devuyst en Michel Jadoul
Auteurs: Chen Li, Marjan van den Akker, Sjaak Brinkkemper en Guido Diepen
1 November 2010 | ARTICLE
Diagnostic accuracy of plasma NT-proBNP levels for excluding cardiac abnormalities in the very elderly
ABSTRACT: BACKGROUND: In the elderly the diagnosis of chronic heart failure is often challenging and the availability of echocardiography can be limited. Plasma levels of NT-proBNP are valuable tools to diagnose patients with heart failure. Howeve...
Auteurs: Bert Vaes, Victoria Delgado, Jeroen Bax, Jean-Marie Degryse, Rudi Gj Westendorp en Jacobijn Gussekloo
Auteurs: L Wennekes, R Hermens, K Aben, R Grol, H Wollersheim, C Punt, PB Ottevanger en H van Krieken