Publicaties

BACKGROUND: Elective single embryo transfer (eSET) enables the prevention of multiple pregnancies after in vitro fertilization (IVF). However, in Europe, the multiple pregnancy rate after IVF remains stable at approximately 23%, with SET occurring...

Bladder cancer is a major health concern for older males in Western populations. About 30 years ago there was a suggestion that nutrition may have a role in the aetiology of the disease. Although the literature has been accumulating since then, ow...

To date, many epidemiological studies have been conducted to examine the association between occupation and bladder cancer incidence. However, results from these studies often have been inconsistent, and significant associations have rarely been f...

We examined the validity of immunohistochemistry for mismatch repair (MMR) proteins in colorectal cancer specimens to identify patients at risk for Lynch syndrome (hereditary nonpolyposis colorectal cancer) and patients with sporadic microsatellit...

BACKGROUND: Clinical practice guidelines bridge the gap between the evidence from literature and clinical practice, and they may provide guidance in ethical, legal and societal dilemmas. To explore the potentials for future international guideline...

OBJECTIVE: To test the validity, reliability and discriminating capacity of an instrument to assess team climate, the Team Climate Inventory (TCI), in a sample of Dutch hospital teams. The TCI is based on a four-factor theory of team climate for i...

Objective:Children born small for gestational age are at increased risk of developing type 2 diabetes in adulthood. The satiety signal leptin that regulates food intake and energy expenditure might be a possible molecular link, as umbilical cord l...

PURPOSE: This study examined the referral process for genetic counseling at a cancer genetics clinic in patients with colorectal cancer and to search for determinants of variation in this referral process. METHODS: Patients who were recently diagn...

The aim of this study was to analyse how patients with mild Alzheimer's disease (AD) cope with the changes they face concerning everyday life and social relations. This study used a grounded theory approach in the analysis of interview data from 1...

BACKGROUND: More so than the traditional socioeconomic indicators, such as education and income, wealth reflects the accumulation of resources and makes socioeconomic ranking manifest and explicitly visible to the outside world. While the lack of ...

Heupbelasting speelt een rol in de ontwikkeling van osteoartrose en beïnvloedt het proces van botremodellering en osseointegratie van het implantaat na het plaatsen van een totale heupprothese (THP). Dit doctoraatsproject behandelt de kwantificati...

The concept of 'patient-friendly' medically assisted reproduction includes a robust set of clinical practice principles, to improve the quality of subfertility care. This concept is an important move away from the sole focus on effectiveness and h...

Hip loading affects bone remodeling and implant fixation. In this study, we have analyzed the effect of subject-specific modeling of hip geometry on muscle activation patterns and hip contact forces during gait, using musculoskeletal modeling, inv...

BACKGROUND: Even in generally wealthy Western countries material deprivation and poverty are not uncommon. There is, however, little data on the prevalence of material deprivation and its associations with health-related dysfunction in older peopl...

Hoe ervaren diabetespatiënten en -verpleegkundigen de educatieprogramma's die sinds enkele jaren in ons land gevolgd kunnen worden? Gaan patiënten na de educatie op een andere manier met hun ziekte om? Verbetert de therapietrouw? Hoe verloopt de s...

We employed recently developed statistical methods to explore the epidemic behaviour of hepatitis C subtype 1a and subtype 3a among injecting drug users (IDUs) in Flanders, Belgium, using new gene sequence data sampled among two geographically dis...

Aims: We aimed to examine the association of cognitive decline with quality of life (QoL) in dementia compared to controls and to determine variables associated with QoL. Methods: Every subject was placed within a specific group depending on their...

In many countries, questions have been raised about the use of evidence-based practice (EBP) in oral health care. The call for an increase in EBP seems to face many obstacles. Only limited empirical studies address these obstacles. We present a qu...

OBJECTIVE: To assess the occurrence of interval breast cancers among those women who attended the mammography screening programme in the Belgian province of Limburg. Interval cancers are tumours that are being diagnosed before the next scheduled s...

OBJECTIVE: to evaluate the impact of a staff-oriented intervention on the number of accidental falls in residents with and without cognitive impairment. DESIGN: clustered randomised controlled trial. METHODS: ten nursing wards from 7 nursing homes...

Epidemiologic investigations often report dose-response associations, which may be combined in meta-analyses. The authors examined how often the log odds, risk, or hazard ratio per unit increase in exposure, and its standard error, can be estimate...

BACKGROUND: We were unable to identify studies that have considered the diffusion of an e-learning programme among a large population of general practitioners. The aim of this study was to investigate the uptake of an e-learning programme introduc...

INTRODUCTION: The aim of this study was to describe how Danish patients and their general practitioners (GPs) perceive physician's use of computers during consultation. MATERIALS AND METHODS: Data were collected between November 2006 and February ...

Dit is een bespreking van een Engelstalige publicatie verschenen in Medical Education die voor het publiek van Vlaamse huisartsen vertaald en ingekort werd

Background: In daily practice serum creatinine measurement still often used as an idex of renal function. The sensitivity of this test however is low. A number of prediction equations have been developed to estimate the GFR using serum creatinine ...

The assessment of fetal growth is an essential component of good antenatal care, especially for twins. The aims of this study are to develop twin-specific intrauterine 'growth' charts, based on cross-sectional birthweight data, for monochorionic a...