Publicaties

Polyploidy and allopolyploidy have played an important role in the evolution of many plants and crops. Several techniques exist to characterize allopolyploid varieties. Analyzing the consequences of genomic reorganization at the gDNA level is a pr...

The total number of primary haematological cancers, diagnosed in the province of Limburg (Belgium) in the period 1998-2005 amounted to 3,198 (1,777 = 56% in males). European standardized incidence rates per 100,000 patient-years in males were 2.7 ...

The objective of this study is to evaluate the impact of International Normalized Ratio testing by point of care devices, on morbidity and mortality of patients treated with oral anticoagulants, in comparison with usual testing in laboratory.A sys...

© OECD 2011. This chapter provides an overview of the descriptive epidemiology of multimorbidity in terms of its prevalence and distribution within the population and its associations with mortality, functional status and quality of life, and heal...

Introduction: Both chronic diseases and cancer are associated with ageing. As the population ages, also the number of older cancer patients with comorbidity will increase dramatically. In the future, general practitioners will be confronted with o...

Achtergrond E r lijkt een gebrek aan een uniforme aanpak bij het keuren van jonge, competitieve sporters en richtlijnen hieromtrent binnen de huisartsenpraktijk. D oel Nagaan wat de beste aanpak is van een gesystematiseerd keuringsonderzoek in een...

Stijn Van de Velde and colleagues describe the African First Aid Materials project, which developed evidence-based guidelines on administering first aid in the African context as well as training materials to support the implementation of the guid...

Defective genomic imprinting is often associated with syndromes that include abnormal growth as a clinical phenotype. However, whether differential methylation at imprinted loci also contributes to nonsyndromic abnormal body weight regulation is y...

Albania is a small south-eastern European country still recovering from almost half a century of a fierce communist regime. While major reform and support have focused on healthcare and higher education (HE) in the past decade, there have not been...

Cervical cancer screening in Belgium is mainly opportunistic with periodic attempts to organize it according to the European guidelines. In the province of Limburg (north-east Belgium), a cervical cytology registry was set up in collaboration with...

We evaluated the performance of the IMMIDIET food frequency questionnaire (FFQ) used to collect dietary data for the Belgian case-control study on bladder cancer. Thirty-seven men and women aged 50 years and older were recruited from the Universit...

Peripheral arterial disease (PAD) is common in older people. An ankle-brachial index (ABI) < 0.9 can be used as an indicator of PAD. Patients with low ABI have increased mortality and a higher risk of serious cardiovascular morbidity. However, bec...

Three genome-wide association studies in Europe and the USA have reported eight urinary bladder cancer (UBC) susceptibility loci. Using extended case and control series and 1000 Genomes imputations of 5 340 737 single-nucleotide polymorphisms (SNP...

Assessment of diabetes care quality increasingly integrates measurements of patient perceptions. With escalating demand for diabetic services, it is critical to evaluate patients' experiences with patient-centred care and their association with ou...

De huisarts wordt steeds meer en steeds beter omringd en ondersteund door wetenschappelijke gegevens die het medisch handelen beter en meer onderbouwen. Dat is een goede evolutie. De realiteit leert echter dat communicatie de belangrijkste hulp is...

Introduction: With the growing number of older cancer patients, the burden of chronic diseases among older cancer patients will become increasingly important. Chronic diseases often interfere with treatment decisions and prognosis for cancer patie...

Introduction: Cancer is largely a disease of older patients. Previous studies on older cancer patients have focussed on the characteristics of this patient group, their ability to tolerate treatment and the use of geriatric assessment tools. Howev...

Cost-effective health care depends on high-quality triage. The most challenging aspect of triage, which GPs confront on a regular basis, is diagnosing rare but serious disease. Failure to shoulder any risk in this situation overloads the health sy...