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1 January 2010 | ARTICLE
Generic and Disease-Specific Measures of Quality of Life in Patients with Mild Alzheimer's Disease
BACKGROUND/AIM: The aim of the study was to investigate the pattern of association of generic and disease-specific quality of life (QoL) scales with standard clinical outcome variables in Alzheimer's disease (AD). METHODS: The participants were 32...
Auteurs: Suvosree Bhattacharya, Asmus Vogel, Marie-Louise H Hansen, Frans B Waldorff et Gunhild Waldemar
Auteurs: Cathy Matheï, Gijs Van Pottelbergh, Pierre Wallemacq et Jean-Marie Degryse
1 January 2010 | ARTICLE
Supporting the dementia family caregiver: the effect of home care intervention on general well-being
OBJECTIVES: Although high volumes of literature have been written on interventions in dementia home care, only a poor efficiency has been proved. Nevertheless, caregivers often express strong feelings of satisfaction about the proposed support. In...
Auteurs: Birgitte Schoenmakers, Frank Buntinx et Jan DeLepeleire
Auteurs: Geert Goderis et Chantal Mathieu
1 December 2009 | ARTICLE
Osteoporosis management: a perspective based on bisphosphonate data from randomised clinical trials and observational databases
AIMS: The efficacy of treatments for osteoporosis can be evaluated using a variety of study designs. This article aims to comprehensively review the evidence for bisphosphonate anti-fracture efficacy in postmenopausal women, discussing the strengt...
Auteurs: Steven Boonen, R Kay, C Cooper, Patrick Haentjens, Dirk Vanderschueren, Filip Callewaert, Koen Milisen et S Ferrari
1 December 2009 | ARTICLE
Cervixcarcinoma screening policy by general practitioners in Limburg (Belgium): A telephonic survey
Yearly about 35 cases of invasive cervical cancer are diagnosed in Limburg (Belgium) of which 90% could have been prevented by adequate screening and follow-up. In 2007 a representative sample of general practitioners in Limburg was questioned by ...
Auteurs: C Mathei, C Steylaerts, G Thijs, E De Jonge, L Op De Beeck, G Orye, G Broeders, E Cloes, B Adriaens, D Lousbergh et F Buntinx
1 December 2009 | ARTICLE
The effect of reminder letters on the uptake of an e-learning programme on dementia: a randomized trial in general practice
BACKGROUND AND AIMS: The aim of the present study was to evaluate whether three reminder letters mailed to GPs after dissemination of a Dementia Guideline increased the GPs' use of the corresponding e-learning programme (ELP). METHODS: Single-blin...
Auteurs: Frans Boch Waldorff, Volkert Siersma, Bente Nielsen, Annette Plesner Steenstrup et Flemming Bro
1 December 2009 | ARTICLE
Successful preliminary walking experiments on a trans-tibial amputee fitted with a powered prosthesis
This paper presents the results of preliminary walking experiments on a transtibial amputee wearing a powered prosthesis. The prosthesis prototype serves as a proof-of-concept implementation for investigating the potential of pleated pneumatic art...
Auteurs: Rino Versluys, Gerlinde Lenaerts, Michael Van Damme, Ilse Jonkers, Anja Desomer, Louis Peeraer, Georges Van der Perre et Dirk Lefeber
1 December 2009 | ARTICLE
Lonely patients in general practice: a call for revealing GPs' emotions? A qualitative study
BACKGROUND: Loneliness is a universal phenomenon that influences one's health and health perception. GPs are confronted with lonely people quite often. Yet, what GPs think of this phenomenon and how they deal with emotions lonely patients evoke is...
Auteurs: Jonne van der Zwet, Marije S Koelewijn-van Loon et Marjan van den Akker
1 December 2009 | ARTICLE
Validity and reliability of the Turkish version of the Hill-Bone compliance to high blood pressure therapy scale for use in primary health care settings
OBJECTIVES: To assess the validity and reliability of the Turkish version of the Hill-Bone compliance to high blood pressure therapy scale for use in primary care in Turkey. METHODS: To develop a Turkish version of the scale, it was translated int...
Auteurs: Melek Karademir, Ismail Hakan Koseoglu, Kevser Vatansever et Marjan Van den Akker
Auteurs: Marijke Alen, Suzanne Kaptein, Tine De Burghgraeve, Johan Neyts, Jan Balzarini et Dominique Schols
1 December 2009 | ARTICLE
Effectiveness of electronic guideline-based implementation systems in ambulatory care settings - a systematic review
Background: Electronic guideline-based decision support systems have been suggested to successfully deliver the knowledge embedded in clinical practice guidelines. A number of studies have already shown positive findings for decision support syste...
Auteurs: Annemie Heselmans, Stijn Van de Velde, Peter Donceel, Bert Aertgeerts et Dirk Ramaekers
25 November 2009 | ARTICLE
Private costs almost equal health care costs when intervening in mild Alzheimer's: a cohort study alongside the DAISY trial
BACKGROUND: Alzheimer's disease is the leading cause of dementia and affects about 25 million people worldwide. Recent studies have evaluated the effect of early interventions for dementia, but few studies have considered private time and transpor...
Auteurs: Rikke Sogaard, Jan Sorensen, Frans B Waldorff, Ane Eckermann, Dorthe V Buss et Gunhild Waldemar
3 November 2009 | ARTICLE
The Role of Hklp2 in the Stabilization and Maintenance of Spindle Bipolarity
Spindle bipolarity relies on a fine balance of forces exerted by various molecular motors [1-4]. In most animal cells, spindle bipolarity requires sustained outward forces to push the spindle poles apart, an activity that is provided by Eg5, a con...
Auteurs: David Vanneste, Masatoshi Takagi, Naoko Imamoto et Isabelle Vernos
1 November 2009 | ARTICLE
Reduction in hormone replacement therapy use and declining breast cancer incidence in the Belgian province of Limburg
Breast cancer is the most common female cancer in Europe, but its incidence and mortality are rapidly changing across Europe. The early termination of the women's health initiative (WHI) trial, after the detection of an increased breast cancer ris...
Auteurs: Patrik Vankrunkelsven, Eliane Kellen, Daniël Lousbergh, Edith Cloes, Lode Op De Beeck, Christel Faes, Liesbeth Bruckers, Raf Mertens, Jan W Coebergh, Flora E Van Leeuwen et Frank Buntinx
Auteurs: Walter Sermeus, Arthur Vleugels, Kris Vanhaecht, Hilde Alewaters, Annemie Glorieux, Eva Van Gerven, Jan Heyrman, Bert Aertgeerts, Jan De Lepeleire et Jan Peers
1 November 2009 | ARTICLE
A randomized clinical trial using an educational intervention demonstrated no effect on interobserver agreement on assessments of functional status
Aim To evaluate the effect of an educational intervention on interobserver agreement of assessments of functional status performed by registered nurses and care assistants in a nursing home and to compare interobserver agreement in persons with a...
Auteurs: Louis Paquay, Jan De Lepeleire, Koen Milisen, M Ylieff et Frank Buntinx
1 November 2009 | ARTICLE
The accuracy of plasma natriuretic peptide levels for diagnosis of cardiac dysfunction and chronic heart failure in community-dwelling elderly: a systematic review
BACKGROUND: measurement of plasma natriuretic peptide levels has been proposed as a simple, accessible test to assist the diagnosis of cardiac dysfunction and heart failure. Most studies have been hospital based and have investigated the relations...
Auteurs: Bert Vaes, Wouter de Ruijter, Jacobijn Gussekloo et Jean-Marie Degryse
11 October 2009 | ARTICLE
Can we import quality tools? a feasibility study of European practice assessment in a country with less organised general practice
BACKGROUND: Quality is on the agenda of European general practice (GP). European researchers have, in collaboration, developed tools to assess quality of GPs. In this feasibility study, we tested the European Practice Assessment (EPA) in a one-off...
Auteurs: Roy Remmen, Luc Seuntjens, Dominique Paulus, Dominique Pestiaux, Klaus Knops et Ann Van den Bruel
Auteurs: Birgitte Schoenmakers
1 October 2009 | ARTICLE
Aberrant pelvis and hip kinematics impair hip loading before and after total hip replacement
Musculoskeletal loading is an important factor affecting the development of osteoarthritis, bone remodelling and primary fixation of total hip replacement (THR). In this study, we analyzed the relation between muscular force, gait kinematics and k...
Auteurs: Gerlinde Lenaerts, Michiel Mulier, Arthur Spaepen, Georges Van der Perre et Ilse Jonkers
Auteurs: Maria Emanuela Albert Goossens, Frank Buntinx et Maurice P Zeegers
1 October 2009 | ARTICLE
Obstacles to the implementation of evidence-based physiotherapy in practice: A focus group-based study in Belgium (Flanders)
Over the past few years concerns have been rising about the use of Evidence-Based Practice (EBP). We explored obstacles among Belgian physiotherapists to the implementation of EBP in clinical work. We used a qualitative research strategy based on ...
Auteurs: Karin Hannes, Filip Staes, Jo Goedhuys et Bert Aertgeerts
1 October 2009 | ARTICLE
Diabetes mellitus type II as a risk factor for depression: a lower than expected risk in a general practice setting
The aim of the present study was to determine whether a diagnosis of diabetes mellitus (DM) in a primary setting is associated with an increased risk of subsequent depression. A retrospective cohort design was used based on the Registration Networ...
Auteurs: S Aarts, M van den Akker, MPJ van Boxtel, J Jolles, B Winkens et JFM Metsemakers
23 September 2009 | ARTICLE
Association between subjective memory complaints and health care utilisation: a three-year follow up.
BACKGROUND: Subjective memory complaints (SMC) are common among elderly patients and little is know about the association between SMC and health care utilisation. Thus, the aim of this study was to investigate health care utilisation during a thre...
Auteurs: Frans Boch Waldorff, Volkert Siersma et Gunhild Waldemar
1 September 2009 | ARTICLE
Factors influencing European GPs' engagement in smoking cessation: a multi-country literature review
BACKGROUND: Smoking cessation advice by GPs is an effective and cost-effective intervention, but is not implemented as widely as it could be. AIM: This wide-ranging Europe-wide literature review, part of the European Union (EU) PESCE (General Prac...
Auteurs: Martine Stead, Kathryn Angus, Ingrid Holme, David Cohen et Gayle Tait
1 September 2009 | ARTICLE
Troubles psychologiques et comportementaux de la démence
Les signes et symptômes comportementaux et psychologiques - SCPD constituent une composante clinique majeure du tableau clinique des démences. Ils peuvent induire une souffrance importante chez les sujets déments et leur entourage. Le but de l’étu...
Auteurs: Gilles Squelard, Pierre Missotten, Michel Ylieff, David Di Notte, Louis Paquay, Frank Buntinx et Jan De Lepeleire
1 September 2009 | ARTICLE
Measuring Rebelliousness and Predicting Health Behaviour and Outcomes An Investigation of the Construct Validity of the Social Reactivity Scale
The Social Reactivity Scale is a questionnaire measure of individual differences in rebelliousness. The associations between rebelliousness, health behaviours and health outcomes were examined in two Dutch samples by means of cross-sectional surve...
Auteurs: G Klabbers, H Bosma, M van den Akker, MPJ van Boxtel, GIJM Kempen, MR McDermott et J Th M Van Eijk
1 September 2009 | ARTICLE
The attitude of Belgian social insurance physicians towards evidence-based practice and clinical practice guidelines
Background: Evidence-based medicine has broadened its scope and is starting to reach insurance medicine. Although still in its initial stages, physicians in the area of insurance medicine should keep up-to-date with the evidence on various disease...
Auteurs: Annemie Heselmans, Peter Donceel, Bert Aertgeerts, Stijn Van de Velde et Dirk Ramaekers
1 September 2009 | ARTICLE
Parent-of-origin specific linkage and association of the IGF2 gene region with birth weight and adult metabolic risk factors
OBJECTIVE: The maternally imprinted insulin-like growth factor 2 (IGF2) gene is an important fetal growth factor and is also suggested to have postnatal metabolic effects. In this study, we examined whether common polymorphisms in IGF2 (6815_6819d...
Auteurs: NY Souren, ADC Paulussen, A Steyls, RJF Loos, RD Brandao, M Gielen, HJM Smeets, Gaston Beunen, Robert Fagard, Cathérine Derom, Robert Vlietinck, JP Geraedts et MP Zeegers