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4 November 2022 | ARTICLE
Point-of-care C-reactive protein test results in acute infections in children in primary care: an observational study
Abstract Background Acute infections are a common reason for children to consult primary care. Serious infections are rare but differentiating them from self-limiting illnesses remains challenging. This can lead to inappropriate antibiotic prescri...
Auteurs: Liselore De Rop, Tine De Burghgraeve, An De Sutter, Frank Buntinx et Jan Verbakel
3 November 2022 | ARTICLE
A multi-level perspective on perceived unmet needs for home support in home-dwelling older adults in the Swiss context: a secondary data analysis of a population study
BACKGROUND: Unmet needs for home support occur when any support services perceived by older people as needed are not being received. Not meeting these needs can negatively impact older adults' quality of life, and increase health care utilization,...
Auteurs: Maria Jose Mendieta, Sabina M De Geest, Geert Goderis, Olivia Yip, Mieke Deschodt et Suzanne Dhaini
1 November 2022 | ARTICLE
Diagnostic accuracy of blood tests of inflammation in paediatric appendicitis: a systematic review and meta-analysis
OBJECTIVE: Possible childhood appendicitis is a common emergency presentation. The exact value of blood tests is debated. This study sought to determine the diagnostic accuracy of four blood tests (white cell count (WCC), neutrophil(count or perce...
Auteurs: David Fawkner-Corbett, Gail Hayward, Mohammed Alkhmees, Ann Van den Bruel, Jose M Ordonez-Mena et Gea A Holtman
Auteurs: Hilaire Gbodja Houeninvo, Kefilath Bello, Hashim Hounkpatin et Jean-Paul Dossou
1 November 2022 | ARTICLE
Declining Prevalence of SARS-CoV-2 Antibodies among Vaccinated Nursing Home Residents and Staff Six Months after the Primary BNT162b2 Vaccination Campaign in Belgium: A Prospective Cohort Study
In the SCOPE study, we monitored SARS-CoV-2 antibodies in a national sample of residents and staff from Belgian nursing homes. Here, we report the seroprevalence among infected and infection-naive residents and staff after the primary COVID-19 vac...
Auteurs: Eline Meyers, Ellen Deschepper, Els Duysburgh, Liselore De Rop, Tine De Burghgraeve, Pauline Van Ngoc, Marina Digregorio, Simon Delogne, Anja Coen, Nele De Clercq, Laetitia Buret, Samuel Coenen, An De Sutter, Beatrice Scholtes, Jan Y Verbakel, Piet Cools et Stefan Heytens
1 November 2022 | ARTICLE
Diet or medication in primary care patients with IBS: the DOMINO study - a randomised trial supported by the Belgian Health Care Knowledge Centre (KCE Trials Programme) and the Rome Foundation Research Institute
BACKGROUND: In Europe, IBS is commonly treated with musculotropic spasmolytics (eg, otilonium bromide, OB). In tertiary care, a low fermentable oligosaccharides, disaccharides, monosaccharides and polyols (FODMAP) diet provides significant improve...
Auteurs: Florencia Carbone, Karen Van den Houte, Linde Besard, Celine Tack, Joris Arts, Philip Caenepeel, Hubert Piessevaux, Alain Vandenberghe, Christophe Matthys, Jessica Biesiekierski, Luc Capiau, Steven Ceulemans, Olivier Gernay, Lydia Jones, Sophie Maes, Christian Peetermans, Willem Raat, Jeroen Stubbe, Rudy Van Boxstael, Olivia Vandeput, Sophie Van Steenbergen, Lukas Van Oudenhove, Tim Vanuytsel, Michael Jones et Jan Tack
1 November 2022 | ARTICLE
The Impact of the COVID-19 Pandemic on eHealth Use in the Daily Practice and Life of Dutch-Speaking General Practitioners in Belgium: Qualitative Study With Semistructured Interviews
BACKGROUND: The COVID-19 crisis has led to rapid and far-reaching changes in digital health care, but little is known about what, why, and how changes occurred in eHealth use in Flemish general practice during the pandemic. OBJECTIVE: This study a...
Auteurs: Jan Ismail Yagiz et Geert Goderis
1 November 2022 | ARTICLE
Health care utilization and out-of-pocket expenditure of type 2 diabetic patients: A study in primary care in Bhubaneswar, India
BACKGROUND: Globally, noncommunicable diseases (NCD) demand a higher healthcare expenditure. Among NCDs, diabetes mellitus is often associated with multiple, co-existing chronic conditions. In low- and middle-income countries where most of the hea...
Auteurs: Sandipana Pati, Subhashisa Swain, Marjan van den Akker, Francois G Schellevis, Sanghamitra Pati et Jako S Burgers
Auteurs: Amal Fakha, Merel Leithaus, Bram De Boer, Theo Van Achterberg, Jan Hamers et Hilde Verbeek
Auteurs: Dania Schuetze, Fabian Engler, Cornelia Ploeger, Lisa-R Ulrich, Michaela Hach, Hannah Seipp, Katrin Kuss, Stefan Boesner, Ferdinand M Gerlach, Marjan van den Akker, Antje Erler et Jennifer Engler
28 October 2022 | OTHER
Automated audit & feedback as a tool to implement antibiotic stewardship in primary care using the Intego database

Automated audit & feedback as a tool to implement antibiotic stewardship in primary care using the Intego database

Auteurs: Steve Van den Bulck, Bert Vaes et Jan Verbakel
27 October 2022 | DISSERTATION
Recognition Of Serious Infections in the Elderly (ROSIE)
This research project focuses on the accuracy and added value of new diagnostic tools for ambulatory care, in particular for diagnosing rare but serious infections in elderly (≥65 years). Early recognition and consequent management can improve the...
Auteurs: Thomas Struyf
Auteurs: Ruben Burvenich, Hannelore Dillen et Jan Verbakel
Auteurs: Michaël Christiaan John Van der Elst, Birgitte Schoenmakers, Jos Schols, Ruud Kempen et Jan De Lepeleire
17 October 2022 | ARTICLE
Adverse events of iron and/or erythropoiesis-stimulating agent therapy in preoperatively anemic elective surgery patients: a systematic review
BACKGROUND: Iron supplementation and erythropoiesis-stimulating agent (ESA) administration represent the hallmark therapies in preoperative anemia treatment, as reflected in a set of evidence-based treatment recommendations made during the 2018 In...
Auteurs: Jorien Laermans, Hans Van Remoortel, Bert Avau, Geertruida Bekkering, Jorgen Georgsen, Paola Maria Manzini, Patrick Meybohm, Yves Ozier, Emmy De Buck, Veerle Compernolle et Philippe Vandekerckhove
1 October 2022 | ARTICLE
Do doctors and other healthcare professionals know overdiagnosis in screening and how are they dealing with it? A protocol for a mixed methods systematic review
INTRODUCTION: Overdiagnosis is the diagnosis of a disease that would never have caused any symptom or problem. It is a harmful side effect of screening and may lead to unnecessary treatment, costs and emotional drawbacks. Doctors and other healthc...
Auteurs: Veerle Piessens, Stefan Heytens, Ann Van Den Bruel, Ann Van Hecke et An De Sutter
Auteurs: K Nicholson, T Makovski, M van den Akker et S Stranges
Auteurs: V Gorasso, J Van derHeyden, R De Pauw, I Pelgrims, K De Ridder, S Vandevijvere, S Vansteelandt, B Vaes, D De Smedt et B Devleesschauwer
Auteurs: A Page, J Verbakel, J Verhaeghe, Y Latul, S Housmans et J Deprest
Auteurs: N Conrad, G Verbeke, G Molenberghs, L Goetschalckx, T Callender, K Rahimi, JC Mason, JJV McMurray et JY Verbakel
Auteurs: V Gorasso, J Van der Heyden, R De Pauw, I Pelgrims, K De Ridder, S Vandevijvere, S Vansteelandt, B Vaes, D De Smedt et B Devleesschauwer
1 October 2022 | ARTICLE
Risk assessment for endometrial cancer in women with abnormal vaginal bleeding: Results from the prospective IETA-1 cohort study
OBJECTIVE: To investigate the association between personal history, anthropometric features and lifestyle characteristics and endometrial malignancy in women with abnormal vaginal bleeding. METHODS: Prospective observational cohort assessed by des...
Auteurs: Jan Yvan Verbakel, Ruben Heremans, Laure Wynants, Elisabeth Epstein, Bavo De Cock, Maria Angela Pascual, Francesco Paolo Giuseppe Leone, Povilas Sladkevicius, Juan Luis Alcazar, Catherine Van Pachterbeke, Ligita Jokubkiene, Robert Fruscio, Tom Bourne, Ben Van Calster, Dirk Timmerman et Thierry Van den Bosch
Auteurs: Hannelore Dillen, Geertruida Bekkering, Sofie Gijsbers, Yannick Vande Weygaerde, Sarah Haesevoets, Maarten Van Herck, David Bos, Ann Li, Henricus Gosselink, Thierry Troosters et Jan Verbakel
23 September 2022 | ARTICLE
Evolution of benzodiazepine receptor agonist prescriptions in general practice: A registry-based study

BACKGROUND: Contrary to most European guidelines, benzodiazepine receptor agonists (BZRA) are often used continuously at a low dosage, being the most common form of long-term use. In Belgium, BZRA use is monitored by analyzing self-report data ...

Auteurs: Kristien Coteur, Pavlos Mamouris, Bert Vaes, Marc Van Nuland, Catharina Mathei et Birgitte Schoenmakers
20 September 2022 | ARTICLE
Determining factors associated with cholera disease in Ethiopia using Bayesian hierarchical modeling
BACKGROUND: Cholera is a diarrheal disease caused by infection of the intestine with the gram-negative bacteria Vibrio cholera. It is caused by the ingestion of food or water and infected all age groups. This study aimed at identifying risk factor...
Auteurs: Tsigereda Tilahun Letta, Denekew Bitew Belay et Endale Alemayehu Ali
Auteurs: Lotte Timmermans, Dagje Boeykens, Mustafa Muhammed Sirimsi, Peter Decat, Veerle Foulon, Ann Van Hecke, Mieke Vermandere et Birgitte Schoenmakers
16 September 2022 | ARTICLE
Digital participatory workshops with patients and health professionals to develop an intervention for the management of polypharmacy: results from a mixed-methods evaluation and methodological conclusions.
BACKGROUND: In the COVID-19 pandemic, numerous researchers postponed their patient and public involvement (PPI) activities. This was mainly due to assumptions on patients' willingness and skills to participate digitally. In fact, digital PPI works...
Auteurs: Jennifer Engler, Franziska Brosse, Truc Sophia Dinh, Astrid-Alexandra Klein, Maria-Sophie Brueckle, Jenny Petermann, Christiane Muth, Karola Mergenthal, Marjan van den Akker et Karen Voigt
Auteurs: Julie Domen, I Guler, Liese SWARTENBROEKX JANSSENS et Birgitte Schoenmakers
Auteurs: Simon Beerten, Jan Vandamme, jonas Crèvecoeur, steve Van den Bulck, bert Aertgeerts, nicolas Delvaux, gijs Van Pottelbergh, mieke Vermandere, laura Tops, thomas Neyens et bert Vaes