Publicaties

Een overzicht van alle publicaties van de onderzoekers bij Intego

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18 February 2022 | ARTICLE

Flemish population-based cancer screening programs: impact of COVID-19 related shutdown on short-term key performance indicators

Auteurs: Svetlana Jidkova, Sarah Hoeck, Eliane Kellen, Saskia le Cessie en Mathijs C Goossens

4 February 2022 | ARTICLE

Goal-oriented care for patients with chronic conditions or multimorbidity in primary care: A scoping review and concept analysis

BACKGROUND: The healthcare system is faced by an ageing population, increase in chronic conditions and multimorbidity. Multimorbid patients are faced with multiple parallel care processes leading to a risk of fragmented care. These problems relate...

Auteurs: Dagje Boeykens, Pauline Boeckxstaens, An De Sutter, Lies Lahousse, Peter Pype, Patricia De Vriendt, Dominique Van de Velde en the Primary Care Academy

2 February 2022 | OTHER

INSPIRE: implementation and evaluation of a nurse-led integrated care model for home-dwelling older adults.

Auteurs: Maria Jose Mendieta Jara, Mieke Deschodt, Olivia Yip en Sabina De Geest

2 February 2022 | DISSERTATION

Frailty in later life: Focus on assessment, life course and context

Auteurs: Michaël Christiaan John Van der Elst

1 February 2022 | ARTICLE

Care practices of specialized outpatient pediatric palliative care teams in collaboration with parents: Results of participatory observations

BACKGROUND: Collaboration between parents and professional care providers is an essential part of pediatric palliative care. As children are embedded in family systems and many of the patients are not able to communicate verbally, their parents ar...

Auteurs: Dania Schuetze, Cornelia Ploeger, Michaela Hach, Hannah Seipp, Katrin Kuss, Stefan Bosner, Ferdinand M Gerlach, Marjan van den Akker, Antje Erler en Jennifer Engler

1 February 2022 | ARTICLE

Prospective SARS-CoV-2 cohort study among primary health care providers during the second COVID-19 wave in Flanders, Belgium

BACKGROUND: Primary health care providers (PHCPs) are assumed to be at high risk of a COVID-19 infection, as they are exposed to patients with usually less personal protective equipment (PPE) than other frontline health care workers (HCWs). Nevert...

Auteurs: Joachim Marien, Ann Ceulemans, Diana Bakokimi, Christine Lammens, Margareta Ieven, Stefan Heytens, An De Sutter, Jan Y Verbakel, Ann Van den Bruel, Herman Goossens, Pierre Van Damme, Kevin K Arien en Samuel Coenen

29 January 2022 | ARTICLE

COVID-19 cases, hospitalizations and deaths in Belgian nursing homes: results of a surveillance conducted between April and December 2020

BACKGROUND: In Belgium, the first COVID-19 death was reported on 10 March 2020. Nursing home (NH) residents are particularly vulnerable for COVID-19, making it essential to follow-up the spread of COVID-19 in this setting. This manuscript describe...

Auteurs: Eline Vandael, Katrien Latour, Esma Islamaj, Laura Int Panis, Milena Callies, Freek Haarhuis, Kristiaan Proesmans, Brecht Devleesschauwer, Javiera Rebolledo Gonzalez, Alice Hannecart, Romain Mahieu, Louise de Viron, Etienne De Clercq, Anne Kongs, Naima Hammami, Jean-Marc Francois, Dominique Dubourg, Sarah Henz, Boudewijn Catry en Sara Dequeker

20 January 2022 | ARTICLE

The Impact of Dementia's Affiliate Stigma on the Mental Health of Relatives: A Cross Section Survey

OBJECTIVE: To determine the impact of the affiliate stigma on mental well-being of relatives caring for a person with dementia. DESIGN: The study was conducted in a cross sectional design. SETTING: The study was conducted in a public setting, addr...

Auteurs: Pauline van den Bossche en Birgitte Schoenmakers

20 January 2022 | OTHER

Evaluation of Point of Care Tests in primary care: bridging the gap

Diagnostic testing forms the backbone of a large proportion of public healthcare, informing decisions about treatment, specialty referral and hospital admission. Over the past few decades, diagnostic technologies have become cheaper, smaller, an...

Auteurs: Jan Verbakel

19 January 2022 | ARTICLE

Response to Schell and colleagues

Auteurs: Bogda Koczwara, Laura Deckx, Shahid Ullah en Marjan van den Akker

11 January 2022 | ARTICLE

Trends in prevalence and incidence of registered dementia and trends in multimorbidity among patients with dementia in general practice in Flanders, Belgium, 2000-2021: a registry-based, retrospective, longitudinal cohort study

OBJECTIVES: With the ageing of our population, it seems plausible that the prevalence of both dementia and multimorbidity will increase in the following decades. The aim of this study is to examine the trends in prevalence and incidence of regi...

Auteurs: Simon Gabriel Beerten, Antje Helsen, Jan De Lepeleire, Frans Boch Waldorff en Bert Vaes

10 January 2022 | ARTICLE

Control in the Hospital by Extensive Clinical rules for Unplanned hospitalizations in older Patients (CHECkUP); study design of a multicentre randomized study

BACKGROUND: Due to ageing of the population the incidence of multimorbidity and polypharmacy is rising. Polypharmacy is a risk factor for medication-related (re)admission and therefore places a significant burden on the healthcare system. The repo...

Auteurs: Aimee EMJH Linkens, Vanja Milosevic, Noemi van Nie, Anne Zwietering, Peter W de Leeuw, Marjan van den Akker, Jos MGA Schols, Silvia MAA Evers, Carlota Mestres Gonzalvo, Bjorn Winkens, Bob PA van de Loo, Louis de Wolf, Lucretia Peeters, Monique de Ree, Bart Spaetgens, Kim PGM Hurkens en Hugo M van der Kuy

3 January 2022 | ARTICLE

Using Belgian pharmacy dispensing data to assess antibiotic use for children in ambulatory care

BACKGROUND: The desired effect of antibiotics is compromised by the rapid escalation of antimicrobial resistance. Children are particularly at high-risk for unnecessary antibiotic prescribing, which is owing to clinicians' diagnostic uncertainty c...

Auteurs: Hannelore Dillen, Ruben Burvenich, Tine De Burghgraeve en Jan Y Verbakel

1 January 2022 | ARTICLE

Everyday Lives of Middle-Aged Persons with Multimorbidity: A Mixed Methods Systematic Review

The healthcare burden of patients with multimorbidity may negatively affect their family lives, leisure time and professional activities. This mixed methods systematic review synthesizes studies to assess how multimorbidity affects the everyday li...

Auteurs: Ana Isabel Gonzalez-Gonzalez, Robin Bruenn, Julia Nothacker, Christine Schwarz, Edris Nury, Truc Sophia Dinh, Maria-Sophie Brueckle, Mirjam Dieckelmann, Beate Sigrid Mueller en Marjan van den Akker

1 January 2022 | ARTICLE

The Effects of Heatwaves on Human Morbidity in Primary Care Settings: A Case-Crossover Study

PURPOSE: This study assesses the potential acute effects of heatwaves on human morbidities in primary care settings. METHODS: We performed a time-stratified case-crossover study to assess the acute effects of heatwaves on selected morbidities in p...

Auteurs: Mahmoud Alsaiqali, Katrien De Troeyer, Lidia Casas, Rafiq Hamdi, Christel Faes en Gijs Van Pottelbergh

1 January 2022 | OTHER

The long and bumpy road to integrated care: lessons from the Leuven integrated care project in Belgium

Auteurs: Marie Van de Putte en Gijs Van Pottelbergh

1 January 2022 | ARTICLE

Resilience in advanced cancer caregiving. A systematic review and meta-synthesis

Background: Close relatives provide much of the care to people with cancer. As resilience can shield family caregivers from mental health problems, there has been a burgeoning interest in resilience-promoting interventions. However, the evidence n...

Auteurs: Sophie Opsomer, Emelien Lauwerier, Jan De Lepeleire en Peter Pype

1 January 2022 | ARTICLE

Antibiotic prescribing rate after optimal near-patient C-reactive protein testing in acutely ill children presenting to ambulatory care (ARON project): protocol for a cluster-randomized pragmatic trial

INTRODUCTION: Children become ill quite often, mainly because of infections, most of which can be managed in the community. Many children are prescribed antibiotics which contributes to antimicrobial resistance and reinforces health-seeking behavi...

Auteurs: Jan Yvan Jos Verbakel, Tine De Burghgraeve, Ann Van den Bruel, Samuel Coenen, Sibyl Anthierens, Louise Joly, Annouschka Laenen, Jeroen Luyten en An De Sutter

1 January 2022 | ARTICLE

GPs’ perspectives on diagnosing childhood urinary tract infections: a qualitative study

BACKGROUND: Diagnosis and management of childhood urinary tract infection (UTI) is challenging in general practice because of a range of factors. AIM: To explore GPs' perspectives concerning the barriers to and facilitators for diagnosis and manag...

Auteurs: Hanne Boon, Ann Van den Bruel en Jan Verbakel

1 January 2022 | ARTICLE

Thoracic imaging tests for the diagnosis of COVID-19

BACKGROUND: Our March 2021 edition of this review showed thoracic imaging computed tomography (CT) to be sensitive and moderately specific in diagnosing COVID-19 pneumonia. This new edition is an update of the review. OBJECTIVES: Our objectives we...

Auteurs: Sanam Ebrahimzadeh, Nayaar Islam, Haben Dawit, Jean-Paul Salameh, Sakib Kazi, Nicholas Fabiano, Lee Treanor, Marissa Absi, Faraz Ahmad, Paul Rooprai, Ahmed Al Khalil, Kelly Harper, Neil Kamra, Mariska MG Leeflang, Lotty Hooft, Christian B van der Pol, Ross Prager, Samanjit S Hare, Carole Dennie, Rene Spijker, Jonathan J Deeks, Jacqueline Dinnes, Kevin Jenniskens, Daniel A Korevaar, Jeremie F Cohen, Ann Van den Bruel, Yemisi Takwoingi, Janneke van de Wijgert, Junfeng Wang, Elena Pena, Sandra Sabongui en Matthew DF McInnes

1 January 2022 | ARTICLE

Signs and symptoms to determine if a patient presenting in primary care or hospital outpatient settings has COVID‐19

Abstract - Background COVID‐19 illness is highly variable, ranging from infection with no symptoms through to pneumonia and life‐threatening consequences. Symptoms such as fever, cough, or loss of sense of smell (anosmia) or taste (ageusia), can h...

Auteurs: T Struyf, JJ Deeks, J Dinnes, Y Takwoingi, C Davenport, MMG Leeflang, R Spijker, L Hooft, D Emperador, J Domen en et al.

1 January 2022 | ARTICLE

Use of an electronic medication management support system in patients with polypharmacy in general practice: study protocol of a quantitative process evaluation of the AdAM trial

BACKGROUND: Interventional studies on polypharmacy often fail to significantly improve patient-relevant outcomes, or confine themselves to measuring surrogate parameters. Interventions and settings are complex, with many factors affecting results....

Auteurs: Robin Bruenn, Dorothea Lemke, Kiran Chapidi, Juliane Koeberlein-Neu, Alexandra Piotrowski, Sara Soeling, Wolfgang Greiner, Petra Kellermann-Muehlhoff, Nina Timmesfeld, Marjan van den Akker en Christiane Muth

1 January 2022 | ARTICLE

Evidence-Based Decision Support for a Structured Care Program on Polypharmacy in Multimorbidity: A Guideline Upgrade Based on a Realist Synthesis

Evidence-based clinical guidelines generally consider single conditions, and rarely multimorbidity. We developed an evidence-based guideline for a structured care program to manage polypharmacy in multimorbidity by using a realist synthesis to upd...

Auteurs: Truc Sophia Dinh, Maria-Sophie Brueckle, Ana Isabel Gonzalez-Gonzalez, Joachim Fessler, Ursula Marschall, Manfred Schubert-Zsilavesz, Ferdinand M Gerlach, Sebastian Harder, Marjan van den Akker, Ingrid Schubert en Christiane Muth

1 January 2022 | OTHER

Towards integrated care in the complex healthcare system of Belgium: an implementation strategy based on vicinity networks and a mixed financing model

Auteurs: Marie Van de Putte en Gijs Van Pottelbergh

1 January 2022 | ARTICLE

Point-of-care tests for pediatric urinary tract infections in general practice: a diagnostic accuracy study

BACKGROUND: Early diagnosis of pediatrics urinary tract infections in the outpatient settings is challenging but essential to prevent hospitalization and kidney damage. OBJECTIVE: We aimed to evaluate the diagnostic test accuracy of a selection of...

Auteurs: Hanne A Boon, Tine De Burghgraeve, Jan Y Verbakel en Ann Van den Bruel

1 January 2022 | ARTICLE

Prevalence and incidence of antibodies against SARS-CoV-2 among primary healthcare providers in Belgium during 1 year of the COVID-19 epidemic: prospective cohort study protocol

INTRODUCTION: National SARS-CoV-2 seroprevalence data provide essential information about population exposure to the virus and help predict the future course of the epidemic. Early cohort studies have suggested declines in levels of antibodies in ...

Auteurs: Niels Adriaenssens, Beatrice Scholtes, Robin Bruyndonckx, Jan Y Verbakel, An De Sutter, Stefan Heytens, Ann van den Bruel, Isabelle Desombere, Pierre van Damme, Herman Goossens, Laetitia Buret, Els Duysburgh en Samuel Coenen

1 January 2022 | OTHER

Multimorbidity in middle-aged from the experiences of patients and their health care providers: Protocol of a qualitative stakeholder analysis

Auteurs: Ana Isabel Gonzalez-Gonzalez, Truc Sophia Dinh, Robin Bruenn, Maria-Sophie Brueckle, Christine Schwarz, Mirjam Dieckelmann, Beate Mueller en Marjan Van den Akker

1 January 2022 | ARTICLE

Rapid, point-of-care antigen tests for diagnosis of SARS-CoV-2 infection

BACKGROUND: Accurate rapid diagnostic tests for SARS-CoV-2 infection would be a useful tool to help manage the COVID-19 pandemic. Testing strategies that use rapid antigen tests to detect current infection have the potential to increase access to ...

Auteurs: Jacqueline Dinnes, Pawana Sharma, Sarah Berhane, Susanna S van Wyk, Nicholas Nyaaba, Julie Domen, Melissa Taylor, Jane Cunningham, Clare Davenport, Sabine Dittrich, Devy Emperador, Lotty Hooft, Mariska MG Leeflang, Matthew DF McInnes, Rene Spijker, Jan Y Verbakel, Yemisi Takwoingi, Sian Taylor-Phillips, Ann Van den Bruel en Jonathan J Deeks

1 January 2022 | ARTICLE

Safety of ezetimibe in lipid-lowering treatment: systematic review and meta-analysis of randomised controlled trials and cohort studies

OBJECTIVE: To determine the harms of ezetimibe in people who need lipid-lowering treatment. DESIGN: Systematic review and meta-analysis. DATA SOURCES: Randomised controlled trials and cohort studies. ELIGIBILITY CRITERIA FOR SELECTING STUDIES: Stu...

Auteurs: Nicolas Delvaux, bert Aertgeerts en Geertruida Bekkering

1 January 2022 | ARTICLE

The impact of the Covid-19 pandemic on the incidence of diseases and the provision of primary care: A registry-based study.

INTRODUCTION: The Covid-19 pandemic had a tremendous impact on healthcare but uncertainty remains about the extent to which primary care provision was affected. Therefore, this paper aims to assess the impact on primary care provision and the e...

Auteurs: Steve Van den Bulck, Jonas Crèvecoeur, Bert Aertgeerts, Nicolas Delvaux, Thomas Neyens, Gijs Van Pottelbergh, Patrick Coursier en Bert Vaes