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29 April 2020 | ARTICLE
Magnitude and determinants of multimorbidity and health care utilization among patients attending public versus private primary care: a cross-sectional study from Odisha, India
BACKGROUND: Multimorbidity in primary care is a challenge not only for developing countries but also for low and medium income countries (LMIC). Health services in LMIC countries are being provided by both public and private health care providers....
Auteurs: Sanghamitra Pati, Subhashisa Swain, J Andre Knottnerus, Job FM Metsemakers en Marjan van den Akker
7 April 2020 | ARTICLE
Prediction models for diagnosis and prognosis of covid-19: systematic review and critical appraisal
OBJECTIVE: To review and appraise the validity and usefulness of published and preprint reports of prediction models for diagnosing coronavirus disease 2019 (covid-19) in patients with suspected infection, for prognosis of patients with covid-19, ...
Auteurs: Laure Wynants, Ben Van Calster, Gary S Collins, Richard D Riley, Georg Heinze, Ewoud Schuit, Marc MJ Bonten, Darren L Dahly, Johanna AA Damen, Thomas PA Debray, Valentijn MT de Jong, Maarten De Vos, Paul Dhiman, Maria C Haller, Michael O Harhay, Liesbet Henckaerts, Pauline Heus, Michael Kammer, Nina Kreuzberger, Anna Lohmann, Kim Luijken, Jie Ma, Glen P Martin, David J McLernon, Constanza L Andaur Navarro, Johannes B Reitsma, Jamie C Sergeant, Chunhu Shi, Nicole Skoetz, Luc JM Smits, Kym IE Snell, Matthew Sperrin, René Spijker, Ewout W Steyerberg, Toshihiko Takada, Ioanna Tzoulaki, Sander MJ van Kuijk, Bas van Bussel, Iwan CC van der Horst, Florien S van Royen, Jan Y Verbakel, Christine Wallisch, Jack Wilkinson, Robert Wolff, Lotty Hooft, Karel GM Moons en Maarten van Smeden
1 April 2020 | ARTICLE
Non-contact infrared versus axillary and tympanic thermometers in children attending primary care: a mixed-methods study of accuracy and acceptability
BACKGROUND: Guidelines recommend measuring temperature in children presenting with fever using electronic axillary or tympanic thermometers. Non-contact thermometry offers advantages, yet has not been tested against recommended methods in primary ...
Auteurs: Gail Hayward, Jan Y Verbakel, Fatene Abakar Ismail, George Edwards, Kay Wang, Susannah Fleming, Gea A Holtman, Margaret Glogowska, Elizabeth Morris, Kathryn Curtis en Ann van den Bruel
1 April 2020 | ARTICLE
Zona incerta projection neurons and GABAergic and GLP-1 mechanisms in the nucleus accumbens are involved in the control of gastric function and food intake
OBJECTIVE: Our aim was to explore the effect of γ-aminobutyric acid (GABA) signaling in the nucleus accumbens (NAc) on promoting gastric function and food intake through glucagon-like peptide 1 (GLP-1)-sensitive gastric distension (GD) neurons und...
Auteurs: Qian Wang, Xiaoqian Zhang, Hui Leng, Xiao Luan, Feifei Guo, Xiangrong Sun, Shengli Gao, Xuehuan Liu, Hao Qin en Luo Xu
12 March 2020 | OTHER
resilience in cancer caregiving
Oral presentation of the results of a hermeneutic review.
Auteurs: Sophie Opsomer, Jan De Lepeleire, Emelien Lauwerier en Peter Pype
12 March 2020 | DISSERTATION
Naar een lerend zorgsysteem voor de eerste lijn
Introduction Learning health systems (LHS) enable continuous improvement and innovation in healthcare. In a LHS, knowledge is disseminated and implemented to its users, and routinely collected clinical data is used to evaluate and generate new kno...
Auteurs: Nicolas Delvaux
7 March 2020 | ARTICLE
Malnutrition risk and its association with adverse outcomes in a Belgian cohort of community-dwelling adults aged 80 years and over
Objectives: To investigate the prevalence of malnutrition risk and its association with adverse outcomes in a Belgian cohort of community-dwelling adults aged ≥80 years, a worldwide growing age-group.Methods: In the BELFRAIL cohort, malnutrition r...
Auteurs: Eralda Hegendorfer, Veronika VanAcker, Bert Vaes en Jean-Marie Degryse
Auteurs: Jan Verbakel
Auteurs: Eralda Hegendorfer en Jean-Marie Degryse
1 March 2020 | ARTICLE
The effect of HIV infection and exposure on cognitive development in the first two years of life in Malawi
OBJECTIVES: To assess longitudinal patterns and determinants of cognitive development in infants living with HIV, infants exposed to maternal HIV infection, and HIV-unexposed infants. METHODS: Prospective, community-based cohort study of 555 Malaw...
Auteurs: Thomas Struyf, Queen Dube, Elizabeth A Cromwell, Anna D Sheahan, Robert S Heyderman en Annelies Van Rie
1 March 2020 | ARTICLE
Self-management among community-dwelling people with chronic conditions: Adapting evidence-based group programs using intervention mapping
OBJECTIVE: Self-management is a core theme within chronic care and several evidence-based interventions (EBIs) exist to promote self-management ability. However, these interventions cannot be adapted in a mere copy-paste manner. The current study ...
Auteurs: G Jans, S Lenzen, Gijs Van Pottelbergh, F Dobbels, Ramon Daniels en Evelien Lauwerier
1 March 2020 | ARTICLE
Predictive Accuracy of Frailty Tools for Adverse Outcomes in a Cohort of Adults 80 Years and Older: A Decision Curve Analysis
OBJECTIVES: To compare the predictive performance of 3 frailty identification tools for mortality, hospitalization, and functional decline in adults aged ≥80 years using risk reclassification statistics and decision curve analysis. DESIGN: Populat...
Auteurs: Eralda Hegendoerfer, Bert Vaes, Gijs Van Pottelbergh, Catharina Mathei, Jan Verbakel en Jean-Marie Degryse
13 February 2020 | CONFERENCE PROCEEDING
Infective Endocarditis in Stent-Mounted Bovine Jugular Vein Conduits: Clinical Experience and Evaluation of the Modified Duke Criteria
Objectives: Percutaneous pulmonary valve implantation (PPVI) has proven good hemodynamic results. As infective endocarditis (IE) remains a potential complication and clinical data on the subject are limited we reviewed our patient records to impro...
Auteurs: David Bos, Bjorn Cools, Benedicte Eyskens, Daniel Boshoff, Bart Meyns, Filip Rega, Thierry Sluysmans, Daniel De Wolf, Marc Gewillig en Ruth Heying
3 February 2020 | OTHER
Power of the creative 'third sphere' to conduct HIV research
I presented the concept of my PhD research to Dr Mae Jemison (the first female of colour in space) in an invited 3 minute pitch at an event organised by the Faculty of Social Sciences.
Auteurs: Lynn Hendricks, Karin Hannes, Taryn Young en Cathy Mathei
1 February 2020 | ARTICLE
Effectiveness of a blended care programme for the discontinuation of benzodiazepine use for sleeping problems in primary care: study protocol of a cluster randomised trial, the Big Bird trial
INTRODUCTION: Problematic benzodiazepine use is a global health issue. Although the adverse side effects of long-term use of benzodiazepines are well known, it remains difficult to implement interventions for discontinuation in primary care. Consi...
Auteurs: Kristien Coteur, Marc Van Nuland, Marc Vanmeerbeek, Gilles Henrard, Sibyl Anthierens, Kris Van den Broeck, An De Sutter, Hanne Creupelandt, Dirk Devroey, Roel Van Overmeire, Anne-Marie Offermans, Nadine Kacenelenbogen, Annouschka Laenen en Catharina Mathei
Auteurs: Annemie Heselmans
1 February 2020 | ARTICLE
An inverse association between the Mediterranean diet and bladder cancer risk: a pooled analysis of 13 cohort studies
PURPOSE: The role of diet in bladder carcinogenesis has yet to be established. To date most studies have investigated dietary components individually, rather than as dietary patterns, which may provide stronger evidence for any influence of diet o...
Auteurs: Willem JA Witlox, Frits HM van Osch, Maree Brinkman, Sylvia Jochems, Maria E Goossens, Elisabete Weiderpass, Emily White, Piet A van den Brandt, Graham G Giles, Roger L Milne, Inge Huybrechts, Hans-Olov Adami, Bas Bueno-de-Mesquita, Anke Wesselius en Maurice P Zeegers
1 February 2020 | ARTICLE
Impact of point-of-care panel tests in ambulatory care: a systematic review and meta-analysis
OBJECTIVES: This article summarises all the available evidence on the impact of introducing blood-based point-of-care panel testing (POCT) in ambulatory care on patient outcomes and healthcare processes. DESIGN: Systematic review and meta-analysis...
Auteurs: Clare Goyder, Pui San Tan, Jan Verbakel, Thanusha Ananthakumar, Joseph J Lee, Gail Hayward, Philip J Turner en Ann Van Den Bruel
1 February 2020 | ARTICLE
Development of quality indicators for type 2 diabetes, extractable from the electronic health record of the general physician. A rand-modified Delphi method
AIMS: Type 2 diabetes mellitus is a worldwide cause of significant morbidity and mortality. The general physician (GP) plays an important role in managing this disease and the use of the electronic health record (EHR) can improve quality for type ...
Auteurs: Steve A Van den Bulcka, Patrik Vankrunkelsuen, Geert Goderis, Lien Broekx, Kathleen Dreesen, Laura Ruijten, Dimitri Mpoukowualas en Rosella Hermens
Auteurs: Lisa Hermans, Geert Molenberghs, Geert Verbeke, Michael G Kenward, Pavlos Mamouris en Bert Vaes
28 January 2020 | DISSERTATION
Optimising the non-surgical care for knee osteoarthritis in primary care
Osteoarthritis (OA) is the most common joint disorder worldwide. This slow degenerative disease mainly affects knees, hips or hands. It is the 11th highest contributor to global disability on the WHO list because it often leads to pain, impaired m...
Auteurs: David Spitaels
17 January 2020 | ARTICLE
Tools to assess the trustworthiness of evidence-based point-of-care information for health care professionals: A systematic review
BACKGROUND: User-friendly information at the point of care should be well structured, rapidly accessible, and comprehensive. Also, this information should be trustworthy, as it will be used by health care practitioners to practice evidence-based m...
Auteurs: Gerlinde Lenaerts, Geertruida E Bekkering, Martine Goossens, Leen De Coninck, Nicolas Delvaux, Sam Cordyn, Jef Adriaenssens en Patrick Vankrunkelsven
15 January 2020 | OTHER
Carpal tunnel vision
Auteurs: P Van Bostraeten, S Pilate, F Vandereyken en H Baeten
13 January 2020 | ARTICLE
Point prevalence survey of antimicrobial use and healthcare-associated infections in Belgian acute care hospitals: results of the Global-PPS and ECDC-PPS 2017
BACKGROUND: The point prevalence survey of healthcare-associated infections (HAIs) and antimicrobial use organized by the European Centre for Disease Prevention and Control (ECDC-PPS) and the Global Point Prevalence Survey of antimicrobial consump...
Auteurs: Eline Vandael, Katrien Latour, Herman Goossens, Koen Magerman, Nico Drapier, Boudewijn Catry, Ann Versporten en the Belgian Point Prevalence Survey Study Group
12 January 2020 | ARTICLE
The effect of electronic audits and feedback in primary care and factors that contribute to their effectiveness: a systematic review

PURPOSE: The aim of this systematic review was (i) to assess whether electronic audit and feedback (A&F) is effective in primary care and (ii) to evaluate important features concerning content and delivery of the feedback in primary care, inclu...

Auteurs: Steve Van den Bulck, David Spitaels, Bert Vaes, Geert Goderis, Rosella Hermens en Patrik Vankrunkelsven
7 January 2020 | ARTICLE
Computerized clinical decision support system for diabetes in primary care does not improve quality of care: a cluster-randomized controlled trial
BACKGROUND: The EBMeDS system is the computerized clinical decision support (CCDS) system of EBPNet, a national computerized point-of-care information service in Belgium. There is no clear evidence of more complex CCDS systems to manage chronic di...
Auteurs: Annemie Heselmans, Nicolas Delvaux, Annouschka Laenen, Stijn Van de Velde, Dirk Ramaekers, Ilkka Kunnamo en Bert Aertgeerts
1 January 2020 | ARTICLE
Thoracic imaging tests for the diagnosis of COVID-19
BACKGROUND: The respiratory illness caused by SARS-CoV-2 infection continues to present diagnostic challenges. Early research showed thoracic (chest) imaging to be sensitive but not specific in the diagnosis of coronavirus disease 2019 (COVID-19)....
Auteurs: Nayaar Islam, Jean-Paul Salamehl, Mariska MG Leeflang, Lotty Hooft, Trevor A McGrath, Christian B van der Pol, Robert A Frank, Sakib Kazi, Ross Prager, Samanjit S Hare, Carole Dennie, Rene Spijker, Jonathan J Deeks, Jacqueline Dinnes, Kevin Jenniskens, Daniel A Korevaar, Jeremie F Cohen, Ann Van den Bruel, Yemisi Takwoing, Janneke van de Wijgert, Junfeng Wang en Matthew DF McInnes
1 January 2020 | ARTICLE
Impact of comorbidity on health-related quality of life among type 2 diabetic patients in primary care
BACKGROUND: Health-related quality of life (HRQL) is an important outcome for chronic diseases such as diabetes mellitus that is associated with complications, comorbidities, and lifelong care. OBJECTIVES: The present study aims to explore the imp...
Auteurs: Sandipana Pati, Sanghamitra Pati, Marjan van den Akker, F Francois G Schellevis, Sunita Jena en Jako S Burgers
1 January 2020 | ARTICLE
Exploring Cognitive Frailty: Prevalence and Associations with Other Frailty Domains in Older People with Different Degrees of Cognitive Impairment
BACKGROUND: Cognitive frailty has long been defined as the co-occurrence of mild cognitive deficits and physical frailty. However, recently, a new approach to cognitive frailty has been proposed: cognitive frailty as a distinct construct. Nonethel...
Auteurs: Ellen E De Roeck, Anne van der Vorst, Sebastiaan Engelborghs, GA Rixt Zijlstra, Eva Dierckx en D-SCOPE Consortium
Auteurs: Beate S Mueller, Lorenz Uhlmann, Peter Ihle, Christian Stock, Fiona von Buedingen, Martin Beyer, Ferdinand M Gerlach, Rafael Perera, Jose Maria Valderas, Paul Glasziou, Marjan van den Akker en Christiane Muth