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1 January 2019 | ARTICLE
hoe kan het LMN de huisarts ondersteunen?
In 2015-2016 ondervroeg LMN Groot-Leuven alle huisartsenpraktijken in de zorgregio Groot-Leuven om de actuele noden van huisartsen in kaart te brengen (figuur). Kennen huisartsen het LMN? Hoe staan ze tegenover zorgtrajecten? Welke extra ondersteu...
Auteurs: Ann Li en Gijs Van Pottelbergh
Auteurs: Kathryn Nicholson, Tatjana T Makovski, Lauren E Griffith, Parminder Raina, Saverio Stranges en Marjan van den Akker
1 January 2019 | ARTICLE
Analytical accuracy of the handheld PICO monitoring device during emergencies
© Author(s) (or their employer(s)) 2019. No commercial re-use. See rights and permissions. Published by BMJ. Introduction: General practitioners (GP) use few technical devices during emergency situations. They have to recognise which patients hav...
Auteurs: WS Renier, K Erard, M Sabbe, I Hubloue, JY Verbakel, B Aertgeerts en F Buntinx
1 January 2019 | ARTICLE
Is stratification testing for treatment of chronic obstructive pulmonary disease exacerbations cost-effective in primary care? an early cost-utility analysis
OBJECTIVES: Patients with chronic obstructive pulmonary disease (COPD) who experience acute exacerbations usually require treatment with oral steroids or antibiotics, depending on the etiology of the exacerbation. Current management is based on cl...
Auteurs: Lucy Abel, Helen A Dakin, Nia Roberts, Helen F Ashdown, Chris C Butler, Gail Hayward, Ann Van den Bruel, Philip J Turner en Yaling Yang
1 January 2019 | ARTICLE
Identifying brain changes related to cognitive aging using VBM and visual rating scales
Aging is often associated with changes in brain structures as well as in cognitive functions. Structural changes can be visualized with Magnetic Resonance Imaging (MRI) using voxel-based grey matter morphometry (VBM) and visual rating scales to as...
Auteurs: Valentina Pergher, Philippe Demaerel, Olivier Soenen, Carina Saarela, Jos Tournoy, Birgitte Schoenmakers, Mira Karrasch en Marc M Van Hulle
1 January 2019 | ARTICLE
Attributable deaths and disability-adjusted life-years caused by infections with antibiotic-resistant bacteria in the EU and the European Economic Area in 2015: a population-level modelling analysis
BACKGROUND: Infections due to antibiotic-resistant bacteria are threatening modern health care. However, estimating their incidence, complications, and attributable mortality is challenging. We aimed to estimate the burden of infections caused by ...
Auteurs: Alessandro Cassini, Liselotte Diaz Hogberg, Diamantis Plachouras, Annalisa Quattrocchi, Ana Hoxha, Gunnar Skov Simonsen, Melanie Colomb-Cotinat, Mirjam E Kretzschmar, Brecht Devleesschauwer, Michele Cecchini, Driss Ait Ouakrim, Tiago Cravo Oliveira, Marc J Struelens, Carl Suetens, Dominique L Monnet, Reinhild Strauss, Karl Mertens, Thomas Struyf, Boudewijn Catry, Katrien Latour, Ivan Nikolaev Ivanov, Elina Georgieva Dobreva, Arjana Tambic Andrasevic, Silvija Soprek, Ana Budimir, Niki Paphitou, Helena Zemlickova, Stefan Schytte Olsen, Ute Wolff Sonksen, Pille Martin, Marina Ivanova, Outi Lyytikainen, Jari Jalava, Bruno Coignard, Tim Eckmanns, Muna Abu Sin, Sebastian Haller, George L Daikos, Achilleas Gikas, Sotirios Tsiodras, Flora Kontopidou, Akos Toth, Agnes Hajdu, Olafur Guolaugsson, Karl G Kristinsson, Stephen Murchan, Karen Burns, Patrizio Pezzotti Dsstat, Carlo Gagliotti, Uga Dumpis, Agne Liuimiene, Monique Perrin, Michael A Borg, Sabine C de Greeff, Jos CM Monen, Mayke BG Koek, Petter Elstrom, Dorota Zabicka, Aleksander Deptula, Waleria Hryniewicz, Manuela Canica, Paulo Jorge Nogueira, Paulo Andre Fernandes, Vera Manageiro, Gabriel Adrian Popescu, Roxana Ioana Serban, Eva Schreterova, Slavka Litvova, Maria Stefkovicova, Jana Kolman, Irena Klavs, Ales Korosec, Belen Aracil, Angel Asensio, Maria Perez-Vazquez, Hanna Billstrom, Sofie Larsson, Jacqui S Reilly, Alan Johnson en Susan Hopkins
1 January 2019 | ARTICLE
Diagnostic protocols for the management of pregnancy of unknown location: a systematic review and meta-analysis
BACKGROUND: There is no international consensus on how to manage women with a pregnancy of unknown location (PUL). OBJECTIVES: To present a systematic quantitative review summarising the evidence related to management protocols for PUL. SEARCH STR...
Auteurs: S Bobdiwala, S Saso, JY Verbakel, M Al-Memar, B Van Calster, D Timmerman en T Bourne
1 January 2019 | ARTICLE
Systematic screening and assessment of psychosocial well-being and care needs of people with cancer
BACKGROUND: Receiving a diagnosis of cancer and the subsequent related treatments can have a significant impact on an individual's physical and psychosocial well-being. To ensure that cancer care addresses all aspects of well-being, systematic scr...
Auteurs: Bojoura Schouten, Bert Avau, Geertruida Trudy E Bekkering, Patrick Vankrunkelsven, Jeroen Mebis, Johan Hellings en Ann Van Hecke
1 January 2019 | ARTICLE
Metabolic fitness in relation to genetic variation and leukocyte DNA methylation
Metabolic syndrome (MetS) is a highly prevalent condition causing increased risk of several life-threatening diseases. MetS has a pronounced hereditary basis but is also influenced by environmental factors, partly through epigenetic mechanisms. In...
Auteurs: M Caspers, S Blocquiaux, R Charlier, J Lefevre, K De Bock en M Thomis
Auteurs: Elias Van Deun, Walter Sermeus en Geert Goderis
5 December 2018 | DISSERTATION
Towards a disease management plan for heart failure patients in general practice
Introduction Heart failure (HF) is a prevalent health problem with an important economic impact particularly due to frequent (re) hospitalizations. Comprehensive disease management programs (DMPs) integrate all aspects of HF management in a seamle...
Auteurs: M Smeets
1 December 2018 | ARTICLE
Cranial ultrasound and neurophysiological testing to predict neurological outcome in infants born very preterm
AIM: Infants born preterm are at risk of cerebral palsy (CP) and motor or cognitive developmental delay. For clinicians, it is essential to know the relative predictive accuracy of the most commonly used neuroimaging and neurophysiological tests f...
Auteurs: Helen Franckx, Daniele Hasaerts, Koen Huysentruyt en Filip Cools
1 December 2018 | ARTICLE
Frequencies and patterns of laboratory test requests from general practice: a service evaluation to inform point-of-care testing
AIMS: The demand for test requests from general practice to laboratory services remains high. Tests performed at the point of care could reduce turnaround time and speed up clinical decision making. Replicating laboratory testing in the community ...
Auteurs: Thomas R Fanshawe, Jose M Ordonez-Mena, Philip J Turner, Ann Van den Bruel, Brian Shine en Gail N Hayward
1 December 2018 | ARTICLE
A review of the diversity in taxonomy, definitions, scope, and roles in forensic medicine: implications for evidence-based practice
The scope, roles, and tasks of forensic medicine and forensic medical experts currently vary widely between countries and legal systems, which has resulted in barriers to organization, standard setting, and quality assurance for practice in forens...
Auteurs: Putri Dianita Ika Meilia, Michael D Freeman, Herkutanto en Maurice P Zeegers
1 December 2018 | ARTICLE
Various experiences and preferences of Dutch parents in prenatal counseling in extreme prematurity
OBJECTIVE: To investigate experienced and preferred prenatal counseling among parents of extremely premature babies. METHODS: A Dutch nationwide, multicenter, cross-sectional study using an online survey. Surveys were sent to all parents of extrem...
Auteurs: Rosa Geurtzen, Jos Draaisma, Rosella Hermens, Hubertina Scheepers, Mallory Woiski, Arno van Heijst en Marije Hogeveen
1 December 2018 | ARTICLE
Metabolic control in adolescents with type 1 diabetes: Looking at the role of perceived consistent parenting support of self-care
© 2018 EDP Sciences, SETE. Objectives: Different parenting practices contribute differently to the development of adolescent self-care. However, little is known about the impact of consistent parenting practices on adolescent self-care and metabol...
Auteurs: J Pelicand, D Charlier, M Maes, S Henrard en I Aujoulat
1 December 2018 | ARTICLE
Cooling and Comfort: The COMFORTNeo-scale during therapeutic hypothermia after perinatal asphyxia
© 2018 The therapeutic effect of moderate hypothermia in infants with HIE after perinatal asphyxia can be counteracted by stress which should therefore be minimized. Objective: of study was to gain insight in the COMFORTNeo-scale to measure stress...
Auteurs: AJ Brouwer, DH Been-Emanuel, TR de Haan, F Groenendaal, JM Wielenga, AH van Kaam, HL van Straaten, I Zonnenberg, PH Dijk, J Dudink, M Rijken, A van Heijst, KP Dijkman, F Cools, A Zecic, Z Hannink, K Ruhe, M Jaspers, R Dekker, Y Stuijk en S Lagerweij
1 December 2018 | ARTICLE
National cancer control plans
Auteurs: Brian D Nicholson, Bethany Shinkins, Sarah Price, Jan Y Verbakel en Sam Merriel
1 December 2018 | ARTICLE
Reporting and Interpreting Decision Curve Analysis: A Guide for Investigators
CONTEXT: Urologists regularly develop clinical risk prediction models to support clinical decisions. In contrast to traditional performance measures, decision curve analysis (DCA) can assess the utility of models for decision making. DCA plots net...
Auteurs: Ben Van Calster, Laure Wynants, Jan FM Verbeek, Jan Y Verbakel, Evangelia Christodoulou, Andrew J Vickers, Monique J Roobol en Ewout W Steyerberg
1 December 2018 | ARTICLE
Alpha-blockers for uncomplicated ureteral stones: a clinical practice guideline
OBJECTIVE: To develop an evidence-based recommendation concerning the use of α-blockers for uncomplicated ureteric stones based on an up-to-date Cochrane review, as the role of medical expulsive therapy for uncomplicated ureteric stones remains co...
Auteurs: Mieke Vermandere, Ton Kuijpers, Jako Burgers, Ilkka Kunnamo, Jan van Lieshout, Emma Wallace, Joan Vlayen, Elizabeth Schoenfeld, Reed Siemieniuk, Lyndal Trevena, Xiaoye Zhu, Francis Verermen, Ben Neuschwander, Philipp Dahm, Kari Tikkinen, Kris Aubrey-Bassler, Robin Vernooij, Bert Aertgeerts en Geertruida Bekkering
22 November 2018 | ARTICLE
Stigma reduction in relation to HIV test uptake in low- and middle-income countries: a realist review
Background: This realist review was conducted to understand how stigma is reduced in relation to HIV test uptake in low- and middle-income countries (LMICs). Methods: A systematic search of eight databases resulted in 34 articles considered for sy...
Auteurs: Subash Thapa, Karin Hannes, Margaret Cargo, Anne Buve, Sanne Peters, Stephanie Dauphin en Cat Matheï
Auteurs: Bram Pussig, Lodewijk Pas, Mieke Vermandere, Catharina Matheï en bert Aertgeerts
15 November 2018 | ARTICLE
Antimicrobial use in European long-term care facilities: results from the third point prevalence survey of healthcare-associated infections and antimicrobial use, 2016 to 2017
Antimicrobials are commonly prescribed and contribute to the development of antimicrobial resistance in long-term care facilities (LTCFs). In 2010, the European Centre for Disease Prevention and Control initiated point prevalence surveys (PPS) of ...
Auteurs: Enrico Ricchizzi, Katrien Latour, Tommi Karki, Rossella Buttazzit, Beatrice Jans, Maria Luisa Moro, Olivia Aya Nakitanda, Diamantis Plachouras, Dominique L Monnet, Carl Suetens en Pete Kinross
15 November 2018 | ARTICLE
Prevalence of healthcare-associated infections, estimated incidence and composite antimicrobial resistance index in acute care hospitals and long-term care facilities: results from two European point prevalence surveys, 2016 to 2017
Point prevalence surveys of healthcare-associated infections (HAI) and antimicrobial use in the European Union and European Economic Area (EU/EEA) from 2016 to 2017 included 310,755 patients from 1,209 acute care hospitals (ACH) in 28 countries an...
Auteurs: Carl Suetens, Katrien Latour, Tommi Karki, Enrico Ricchizzi, Pete Kinross, Maria Luisa Moro, Beatrice Jans, Susan Hopkins, Sonja Hansen, Outi Lyytikainen, Jacqui Reilly, Aleksander Deptula, Walter Zingg, Diamantis Plachouras en Dominique L Monnet
Auteurs: Thijs Vandenberk, Caroline Pelckmans, Christophe Mortelmans, Haelst Ruth Van, Tine Proesmans, Valerie Storms, Inge M Thijs, Bert Vaes en Pieter M Vandervoort
Auteurs: Thijs Vandenberk, Caroline Pelckmans, Christophe Mortelmans, Ruth Van Haelst, Valerie Storms, Inge M Thijs, Bert Vaes en Pieter M Vandervoort
6 November 2018 | ARTICLE
Time trends in statin use and incidence of recurrent cardiovascular events in secondary prevention between 1999 and 2013: a registry-based study

BACKGROUND: The current study evaluated time trends of statin use and incidence of recurrent CVD in secondary prevention from 1999 to 2013 and investigated which factors were associated with statin use in secondary prevention. METHODS: Intego i...

Auteurs: Nele Laleman, Severine Henrard, Marjan van den Akker, Geert Goderis, Frank Buntinx, Gijs Van Pottelbergh en Bert Vaes
1 November 2018 | ARTICLE
Antimicrobial use in European acute care hospitals: results from the second point prevalence survey (PPS) of healthcare-associated infections and antimicrobial use, 2016 to 2017.
Antimicrobial agents used to treat infections are life-saving. Overuse may result in more frequent adverse effects and emergence of multidrug-resistant microorganisms. In 2016-17, we performed the second point-prevalence survey (PPS) of healthcare...
Auteurs: Diamantis Plachouras, Tommi Kärki, Sonja Hansen, Susan Hopkins, Outi Lyytikäinen, Maria Luisa Moro, Jacqui Reilly, Peter Zarb, Walter Zingg, Pete Kinross, Klaus Weist, Dominique L Monnet, Carl Suetens en The Point Prevalence Survey Study Group
1 November 2018 | ARTICLE
The psychological impact of early pregnancy loss
BACKGROUND: Early pregnancy loss (EPL) is a common event, with scope for long-term personal and societal impact. There are three decades worth of published evidence of profound psychological sequelae in a significant proportion of women. However, ...
Auteurs: Jessica Farren, Nicola Mitchell-Jones, Jan Y Verbakel, Dirk Timmerman, Maria Jalmbrant en Tom Bourne