Publicaties

OBJECTIVES: Medical treatment options and strategies for Crohn's disease (CD) have changed over the past decades. To assess its impact, we studied the evolution of the long-term disease outcome in the Dutch Inflammatory Bowel Disease South Limburg...

Epigenetic mechanisms are dynamic throughout the human lifespan. As gene expression is regulated by the degree of DNA methylation at the promoter region and DNA methylation itself is influenced by several external factors, it is interesting to tak...

Rationale, aims and objectives Questions posed at the point of care (POC) can be answered using POC summarized guidelines. To implement a national POC information resource, we subscribed to a large database of POC summarized guidelines to compleme...

BACKGROUND: Osteoarthritis (OA) is a common musculoskeletal condition that often leads to pain, stiffness and disability. Physiotherapy plays an important role in the management of knee OA, however we hypothesize discordance between physiotherapis...

[This corrects the article DOI: 10.1371/journal.pone.0165127.].

Dit rapport bespreekt de evaluatie van Impulseo of het Impulsfonds. In het kader van het Impulsfonds zijn een pakket maatregelen uitgewerkt om de vestiging en samenwerking van huisartsen aan te moedigen. Via deze maatregelen verleent de Vlaamse o...

OBJECTIVE: To determine the overall publication rates for abstracts presented at two consecutive Nordic Congresses of General Practice and to evaluate determinants for these publication rates. DESIGN: Prospective study. SETTING: MEDLINE (PubMed) a...

Nepalese labor migrants and their wives are considered as at-risk populations for HIV infection. There may be a risk of HIV transmission from the labor migrant and their wives to the general population due to HIV-related risk behaviors, but so far...

OBJECTIFS: Cette étude vise à décrire la mobilisation des représentations ethnoculturelles par des agents et des gestionnaires de santé pour expliquer l'échec partiel d'une politique de santé maternelle et discuter des conséquences potentielles de...

Addiction in adolescence is a complex problem, influenced by a variety of personal and contextual factors. It has substantial individual consequences and an important impact on society. A number of treatment programs for adolescents have been deve...

In January 2015 a multidisciplinary working group of the region Leuven-Tienen was installed to make a management protocol between General Practice and Emergency Services. This was a requirement for financing of guard posts in 2016 decided in the N...

Scientific knowledge is in constant development. Consequently, regular review to assure the trustworthiness of clinical guidelines is required. However, there is still a lack of preferred reporting items of the updating process in updated clinical...

BACKGROUND: Comorbidity is a cause of increased mortality, decreased quality of life and increased use of healthcare services. It is important particularly for physicians and other healthcare providers in primary care settings to evaluate these pa...

OBJECTIVES: Older people may suffer from stigmas linked to cancer and aging. Although some studies suggested that a negative view of cancer may increase the level of depression, such an association has never been studied in the elderly population....

BACKGROUND: Attention deficit hyperactivity disorder (ADHD) is a prevalent neurobiological condition, characterised by behavioral and cognitive symptoms such as inattention, impulsivity and/or excessive activity. The syndrome is commonly accompani...

Guidelines for patients with knee osteoarthritis (OA) are suboptimally implemented in clinical care. To improve guideline adherence, patients' perceived barriers and facilitators in current care were investigated.

Background: It is important for future General Practitioners to acquire competence in communication skills during vocational training. Some interventions have addressed the effectiveness of training in such skills but have yielded varying results....

BACKGROUND: Multi-morbidity and polypharmacy of the elderly population enhances the probability of elderly in residential long-term care facilities experiencing inappropriate medication use. OBJECTIVES: The aim is to systematically review literatu...

Background: Knowledge development depends on an unbiased representation of the available evidence. Selective citation may distort this representation. Recently, some controversy emerged regarding the possible impact of swimming on childhood asthma...