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1 January 2014 | ARTICLE
Multimorbidity's research challenges and priorities from a clinical perspective: The case of 'Mr Curran'
Older patients, suffering from numerous diseases and taking multiple medications are the rule rather than the exception in primary care. A manifold of medical conditions are often associated with poor outcomes, and their multiple medications raise...
Auteurs: Christiane Muth, Martin Beyer, Martin Fortin, Justine Rochon, Frank Oswald, Jose M Valderas, Sebastian Harder, Liam G Glynn, Rafael Perera, Michael Freitag, Roman Kaspar, Jochen Gensichen en Marjan van den Akker
1 January 2014 | ARTICLE
Do psychosocial profiles predict self-rated health, morbidity and mortality in late middle-aged and older people?
Considering many psychosocial health risk factors are interrelated, determining psychosocial health risk might benefit from a more person-centered perspective. This paper explores to what extent a psychosocial profile that combines potentially syn...
Auteurs: Gonnie Klabbers, Hans Bosma, Gertrudis Ignatius Johannes Maria Kempen, Michaela Benzeval, Marjan van den Akker en Jacques Theodorus Margaretha van Eijk
1 January 2014 | ARTICLE
Current guidelines poorly address multimorbidity: pilot of the interaction matrix method
OBJECTIVES: To develop a framework to identify and classify interactions within and among treatments and conditions and to test this framework with guidelines on chronic heart failure (CHF) and its frequent comorbidity. STUDY DESIGN AND SETTING: T...
Auteurs: C Muth, H Kirchner, Marjan van den Akker, M Scherer en PP Glasziou
1 January 2014 | ARTICLE
Four screening instruments for frailty in older patients with and without cancer: a diagnostic study
BACKGROUND: Frailty in older patients might influence treatment decisions. Frailty can be determined using a Comprehensive Geriatric Assessment (CGA), but this is time-consuming and expensive. Therefore we assessed the diagnostic value of four sho...
Auteurs: Ineke HGJ Smets, Gertrudis IJM Kempen, Maryska LG Janssen-Heijnen, Laura Deckx, Frank JVM Buntinx en Marjan van den Akker
Auteurs: Ann Roex, Mieke Vermandere, Sanne Peters, Pieter Stiers, Jens Van Eccelpoel, Marijn Maus en Pieter-Jan Gorissen
1 January 2014 | ARTICLE
Risk factors for loneliness in patients with cancer: A systematic literature review and meta-analysis
OBJECTIVE: To systematically review the literature on the severity and risk factors for loneliness in adult cancer patients. METHODS: We systematically reviewed quantitative studies addressing loneliness in cancer patients. Exclusion criteria were...
Auteurs: Laura Deckx, Marjan van den Akker en Frank Buntinx
Auteurs: Esther Molenaar, Carolien Strouwen, Liesbeth Münks, Samyra Keus, Bastiaan Bloem en Alice Nieuwboer
Auteurs: Magloire Nkosi Mpembi, Samuel Mampunza Ma Miezi, Thierry Matonda Ma Nzuzi, Victoria Kubuta Massamba, Sévérine Henrard, Marie-Pierre De Partz, André Peeters, Jean Macq, Vincent Dubois en Eric Constant
Auteurs: Marleen Finoulst, Patrik Vankrunkelsven, Bart De Strooper en Jan De Lepeleire
1 January 2014 | BOOK CHAPTER
Multimorbidität
Auteurs: C Muth en Marjan van den Akker
1 January 2014 | ARTICLE
The 2014 Updated GOLD Strategy: A Comparison of the Various Scenarios
Background: The 2014 updated Global initiative for chronic Obstructive Lung Disease (GOLD) strategy added the St. George's Respiratory Questionnaire (SGRQ) as the fourth possible symptoms measure. The impact of the suggested tools for symptoms of ...
Auteurs: S Wilke, DE Smid, MA Spruit, DJA Janssen, JWM Muris, T van der Molen, Marjan van den Akker, PW Jones, EFM Wouters en FME Franssen
Auteurs: Marieke Van Vracem, Nele Spruytte en Chantal Van Audenhove
1 January 2014 | ARTICLE
Vaginal birth after a caesarean section: the development of a Western European population-based prediction model for deliveries at term
OBJECTIVE: To develop and internally validate a model that predicts the outcome of an intended vaginal birth after caesarean (VBAC) for a Western European population that can be used to personalise counselling for deliveries at term. DESIGN: Regis...
Auteurs: ENC Schoorel, SMJ van Kuijk, S Melman, JG Nijhuis, LJM Smits, R Aardenburg, K de Boer, FMC Delemarre, IM van Dooren, MTM Franssen, M Kaplan, G Kleiverda, SMI Kuppens, A Kwee, FTH Lim, BWJ Mol, FJME Roumen, JM Sikkema, E Smid-Koopman, H Visser, M Woiski, RPMG Hermens en HCJ Scheepers
Auteurs: Suzan de Visser, Christian Kirchner, Jeroen van Dillen, Rosella Hermens en Mallory Woiski
1 January 2014 | ARTICLE
Finding potentially new multimorbidity patterns of psychiatric and somatic diseases: exploring the use of literature-based discovery in primary care research
BACKGROUND: Multimorbidity, the co-occurrence of two or more chronic medical conditions within a single individual, is increasingly becoming part of daily care of general medical practice. Literature-based discovery may help to investigate the pat...
Auteurs: Rein Vos, Sil Aarts, Erik van Mulligen, Job Metsemakers, Martin P van Boxtel, Frans Verhey en Marjan van den Akker
1 January 2014 | ARTICLE
Hepatitis C virus infection epidemiology among people who inject drugs in Europe: a systematic review of data for scaling up treatment and prevention
People who inject drugs (PWID) are a key population affected by hepatitis C virus (HCV). Treatment options are improving and may enhance prevention; however access for PWID may be poor. The availability in the literature of information on seven ma...
Auteurs: Lucas Wiessing, Marica Ferri, Bart Grady, Maria Kantzanou, Ida Sperle, Katelyn J Cullen, Angelos Hatzakis, Maria Prins, Peter Vickerman, Jeffrey V Lazarus, Vivian D Hope en Cathy Matheï
1 January 2014 | ARTICLE
The relationship between physical performance and cardiac function in an elderly Russian cohort
This study aims to determine the cardiac dysfunction prevalence, to investigate the relationship between the Short Physical Performance Battery (SPPB) test and structural and functional echocardiographic parameters and to determine whether SPPB sc...
Auteurs: Pulod Tadjibaev, Elena Frolova, Natalia Gurina, Jean-Marie Degryse en Bert Vaes
1 January 2014 | ARTICLE
The diagnostic accuracy of the MyDiagnostick to detect atrial fibrillation in primary care
Atrial fibrillation is very common in people aged 65 or older. This condition increases the risk of death, congestive heart failure and thromboembolic conditions. Many patients with atrial fibrillation are asymptomatic and a cerebrovascular accide...
Auteurs: Bert Vaes, Silke Stalpaert, Karen Tavernier, Britt Thaels, Daphne Lapeire, Wilfried Mullens en Jean-Marie Degryse
1 January 2014 | ARTICLE
Triage tests for identifying atrial fibrillation in primary care: a diagnostic accuracy study comparing single-lead ECG and modified BP monitors
OBJECTIVE: New electronic devices offer an opportunity within routine primary care settings for improving the detection of atrial fibrillation (AF), which is a common cardiac arrhythmia and a modifiable risk factor for stroke. We aimed to assess t...
Auteurs: Karen Kearley, Mary Selwood, Ann Van den Bruel, Matthew Thompson, David Mant, FD Richard Hobbs, David Fitzmaurice en Carl Heneghan
1 January 2014 | ARTICLE
The Ariadne principles: how to handle multimorbidity in primary care consultations
Multimorbidity is a health issue mostly dealt with in primary care practice. As a result of their generalist and patient-centered approach, long-lasting relationships with patients, and responsibility for continuity and coordination of care, famil...
Auteurs: Christiane Muth, Marjan van den Akker, Jeanet W Blom, Christian D Mallen, Justine Rochon, Francois G Schellevis, Annette Becker, Martin Beyer, Jochen Gensichen, Hanna Kirchner, Rafael Perera, Alexandra Prados-Torres, Martin Scherer, Ulrich Thiem, Hendrik van den Bussche en Paul P Glasziou
1 January 2014 | ARTICLE
What determines inclusion in the early phase of the type 2 diabetes care trajectory in Belgium?
In 2009, the Belgian National Institute of Health and Disability Insurance established a care trajectory (CT) for a subgroup of type 2 diabetes mellitus patients (T2DM) based on Wagner's chronic care model. The goal of this CT is to optimise the q...
Auteurs: Katrien Vanthomme, Nathalie Bossuyt, Sarah Moreels, Nicole Boffin, Etienne De Clercq, Geert Goderis en Viviane Van Casteren
1 January 2014 | ARTICLE
Optimizing antibiotic prescribing for acutely ill children in primary care (ERNIE2 study protocol, part B): a cluster randomized, factorial controlled trial evaluating the effect of a point-of-care C-reactive protein test and a brief intervention combined with written safety net advice
Despite huge public campaigns, there is still overconsumption of antibiotics in children with self-limiting diseases. Possible explanations may be the physicians' and parents' uncertainty about the gravity of the disease and inadequate communicati...
Auteurs: Marieke B Lemiengre, Jan Verbakel, Tine De Burghgraeve, Bert Aertgeerts, Frans De Baets, Frank Buntinx, An De Sutter en ERNIE 2 collaboration
1 January 2014 | ARTICLE
Diagnosing serious infections in acutely ill children in ambulatory care (ERNIE 2 study protocol, part A): diagnostic accuracy of a clinical decision tree and added value of a point-of-care C-reactive protein test and oxygen saturation
Acute illness is the most common presentation of children to ambulatory care. In contrast, serious infections are rare and often present at an early stage. To avoid complications or death, early recognition and adequate referral are essential. In ...
Auteurs: Jan Verbakel, Marieke B Lemiengre, Tine De Burghgraeve, An De Sutter, Dominique Bullens, Bert Aertgeerts, Frank Buntinx en ERNIE 2 collaboration
1 January 2014 | ARTICLE
Development of quality indicators for an integrated approach of knee osteoarthritis
Objective: Osteoarthritis (OA) is a common cause of disability worldwide. Knee OA care is often suboptimal. A first necessary step in quality improvement is to gain a clear insight into usual care. The aim of the study was, therefore, to develop a...
Auteurs: Lies Grypdonck, Bert Aertgeerts, Frank Luyten, Hubertus Wollersheim, Johan Bellemans, Koen Peers, Sabine Verschueren, Patrik Vankrunkelsven en Rosella Hermens
Auteurs: Mieke Vandewaetere, Dominique Manhaeve, Bert Aertgeerts, Geraldine Clarebout, Jeroen van Merrienboer en Ann Roex
1 January 2014 | ARTICLE
De Vlaamse huisarts anno 2013: op kruissnelheid naar verandering
This study reveals that most GPs still work fulltime in their practice, with limited help for administration and reception. Younger GPs, male GPs and soloists often work fulltime, with 100 to 150 patients per week. GPs considering to stop early, b...
Auteurs: Birgitte Schoenmakers, Bert Aertgeerts, Frank Buntinx, Patrik Vankrunkelsven, Gijs Van Pottelberg en Jan De Lepeleire
1 January 2014 | ARTICLE
Twintig jaar accreditering van huisartsen in België: waar situeren we ons ten opzichte van andere Europese landen?
The Belgian system for continuous professional development (CPD) was established in 1993. When comparing this system to the one in the Netherlands, the United Kingdom and Finland, it appears that the implications of CPD for individual doctors and ...
Auteurs: Ann Roex, Martine Agten, Eva Crauwels, Els De Boeck, Michael Erkens, Stefanie Moermans en Bert Aertgeerts
1 January 2014 | ARTICLE
Accreditering vanuit het electronisch medisch dossier: naar een nieuw model?
Scientific recommendations stipulate how to develop a system of continuous professional development (CPD). These include the application of tailored interventions originating in the individual's learning needs, the use of active learning methods b...
Auteurs: Ann Roex, Martine Agten, Eva Crauwels, Els De Boeck, Michael Erkens, Stefanie Moermans en Bert Aertgeerts
Auteurs: Marleen Finoulst, Patrik Vankrunkelsven en Frank Van der Aa