Publicaties

Dendritic cell-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN) is an important binding receptor for dengue virus (DENV) that recognizes N-glycosylation sites on the viral E-glycoprotein. DENV cannot bind nor infect the h...

OBJECTIVE: Because of its high incidence and improving survival, breast cancer is currently the most prevalent cancer in the world. We reviewed the published literature in our search for modifiable factors valuable as an adjuvant health measure to...

The aim of this descriptive study was to estimate and compare the association between cognitive decline and quality of life (QOL) for 2 groups of dementia patients differing by place of residence: home or institution. Each subject was placed withi...

We developed two indicators to assess the exposure of residents to agricultural pesticide use and applied it in a case-control study on bladder cancer in the province of Limburg, Belgium. The first indicator used a distance-weighted measure of cro...

Het wetenschappelijk onderzoek naar de waarde van diagnostische tests is de laatste jaren sterk in beweging geweest. Het artikel van Ann Van den Bruel et al. is een goed voorbeeld van het resultaat van deze evolutie.

• Meta-analyse op basis van individuele-patiëntdata (IPD-meta-analyse) wordt in toenemende mate toegepast binnen de geneeskunde. De IPD-meta-analyse heeft methodologische voor- en nadelen. • In tegenstelling tot traditionele meta-analyses die zijn...

INTRODUCTION: Stimulant medications are the most effective drugs in the treatment of attention-deficit hyperactivity disorder (ADHD) in children and in adults. However, some patients do not respond to this treatment and other patients suffer from ...

The common sequence variants that have recently been associated with cancer risk are particular to a single cancer type or at most two. Following up on our genome-wide scan of basal cell carcinoma, we found that rs401681[C] on chromosome 5p15.33 s...

Smoking is considered the primary risk factor for bladder cancer. Although smoking prevalence and bladder cancer incidence vary around the world, bladder cancer is on average 4 times more common in males than in females. This article describes the...

Scepsis met betrekking tot nut en noodzaak van vroege opsporing van dementie is niet terecht. Niet alleen de patiënt, maar ook en vooral de mantelzorger is zeer gebaat bij een tijdige diagnose. De huisarts hoeft daarvoor niet per se zijn toevlucht...

BACKGROUND/AIMS: In population studies, different mild cognitive impairment (MCI) definitions have been used to predict dementia at a later stage. This study compared predictive values of different MCI definitions for dementia, and the effect of a...

BACKGROUND: Respiratory failure due to lung immaturity is a major cause of mortality in preterm infants. Although the use of intermittent positive pressure ventilation (IPPV) in neonates with respiratory failure saves lives, its use is associated ...

Background: Although studies are availabel on patients' ideas, concerns and expectations in primary care, there is a scarcity of studies that explore the triad of ideas, concerns, and expectations (ICE) in general practice consultations and the im...

Background: Quality of life (QoL) is an important outcome measure in the treatment of seasonal allergic rhinitis (SAR), a condition for which homeopathy is frequently used. Objective: The assessment of the effect of homeopathic medical prescript...

Success of a total hip replacement is commonly assessed by the Haris Hip Score (HHS), which provides information on pain reduction and regained mobility. Radiographic images provide information relative to the stability of the prosthesis. We use...

We report the follow-up of a cohort of 86 patients who underwent total hip replacement (THR) with custom-made stem prosthesis. Fixation mode, cemented (group 1) or uncemented (group 2) is based on the bone quality. Aspects of physical health and c...

PURPOSE: This paper aims to evaluate the maturity matrix (MM) a facilitated formative self-assessment tool for organisational development in primary care) on satisfaction, differences between GP and staff, the extent to which practice teams worked...

Aging is associated with an increased risk of chronic diseases such as cancer and CVD. Smoking increases the risk of such diseases further. The intake of fruit and vegetables is often promoted as part of a healthy lifestyle to prevent chronic dise...

According to figures of the Intego databank, the incidence of melanoma included 8 per 100,000 patients per year in Flanders (Belgium). Still, since 2001 a downward trend was recorded. This article presents the results of a literature search concer...

Background The International Classification of Functioning, Disability and Health (ICF) is embraced as a framework to conceptualize human functioning and disability. Health professionals choose measures to represent the domains of the framework. T...

We conducted a genome-wide association study on 969 bladder cancer cases and 957 controls from Texas. For fast-track validation, we evaluated 60 SNPs in three additional US populations and validated the top SNP in nine European populations. A miss...

Abstract Objective. To identify the attitudes and perspectives of the family physician towards the caregivers of demented relatives and to describe the caregivers’ satisfaction. Design. Systematic review. Subjects. The studied population consisted...

OBJECTIVE: To picture the profile of type 2 diabetic patients in Belgium and to study the quality of care in the primary care setting, with regard, to multi-factorial approach of the disease. METHODS: Observational study of all known DM2-patients ...

Een snelle diagnose van een myocardinfarct of een acuut coronair syndroom is zeer belangrijk. Om de diagnostische nauwkeurigheid van tien belangrijke klachten en symptomen te bepalen bij al dan niet geselecteerde patiënten werd een systematische r...