Publicaties

A state-of-the-art phylogeny of the human Y-chromosome is an essential tool for forensic genetics. The explosion of whole genome sequencing (WGS) data due to the rapid progress of next generation sequencing facilities is useful to optimize and to ...

BACKGROUND AND OBJECTIVES: Hereditary haemochromatosis (HH) is the most prevalent genetic liver disease, with an incidence of 1/200 to 1/400 in the Caucasian population. HH patients are treated by family physicians as well as different specialists...

CONTEXT: Spiritual distress, including meaninglessness and hopelessness, is common in advanced disease. Spiritual care is a core component of palliative care, yet often neglected by health care professionals owing to the dearth of robust evidence ...

BACKGROUND: In contrast to the postnatal period, little is known about telomere length (TL) during prenatal life. The decrease in placental TL remains unknown, although intra uterine growth retardation and preeclampsia are associated with shorter ...

Objectives: This pilot-study is an evaluation of a psycho-educational program consisting of 11 group sessions for family caregivers of people with dementia. This program is inspired by similar Dutch and German interventions. The main goal of the p...

BACKGROUND: Many European citizens regularly consult homeopathic doctors. Especially for children there is very little data available about the reasons they visit a homeopathic doctor. What are the expectations of the parents consulting a Homeopat...

BACKGROUND: Many patients throughout the world consult homeopathic medical doctors. Using a similar methodology as in a first survey published in 2002 a second survey was done including 919 adults receiving homeopathic treatment in six European co...

This systematic review evaluated micronutrient intake inadequacy of ten micronutrients for adult ethnic minority populations residing in Europe. Pubmed was searched for studies, related references were checked and experts consulted. Ten studies we...

Genome-wide association studies (GWAS) of urinary bladder cancer (UBC) have yielded common variants at 12 loci that associate with risk of the disease. We report here the results of a GWAS of UBC including 1670 UBC cases and 90 180 controls, follo...

The role of home nurses as providers of health care has changed and will continue to change. To guide appropriate decision making and future policy planning, it is important to have a clear picture of the activity profile of home nurses. A systema...

For localized prostate cancer several treatment options are available. Patient decision aids can help patients in making a deliberative, personalized health choice in close collaboration with their physician. The aim of this research was to identi...

The importance of sharing decisions is increasingly acknowledged. Information plays a crucial role in the shared decision making (SDM)process. Sharing of information between patient and physician is a vital step to achieve informed preferences and...

Prenatal polyunsaturated fatty acid (PUFA) concentrations may be involved in the prenatal programming of adiposity. In this study we therefore explored the association between maternal PUFA concentrations, measured up to four times during pregnanc...

Rationale: The OSCE has become one of the most important assessment methods of health professionals’ communication. Although the format has been used for almost forty years, there are still unsolved questions. This symposium will enable five key c...

Rationale: Communication skills training has become increasingly integrated into the education of health care professionals (e.g. physicians, nurses, physiotherapists, pharmacists, etc.). In addition to teaching communication skills, there are im...

BACKGROUND: A health technology assessment (HTA) of left ventricular assist devices (LVADs) as destination therapy in patients with end-stage heart failure was commissioned by the Dutch Health Care Insurance Board [College voor Zorgverzekeringen (...