Publicaties

Een overzicht van alle publicaties van de onderzoekers bij Intego

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1 September 2014 | OTHER

Patient preferences for education strategies in individuals with a chronic disease

Auteurs: Emelien Lauwerier, Ann Deschamps, Gijs Van Pottelbergh, Sandra Martin, Nele Zupancic, Annelies Vandamme, and Philip Moons

1 September 2014 | ARTICLE

Drug prescriptions unadapted to the renal function in patients aged 80 years and older (a.)

Background: Drug-related problems are common in older people. Often they are related to low estimated glomerular filtration rate (eGFR), which has a high prevalence among older adults. The aim of this study was to investigate inappropriate drug pr...

Auteurs: Gijs Van Pottelbergh, An Mertens, Majda Azermai, Bert Vaes, Wim Adriaensen, Cathy Matheï, Pierre Wallemacq, and Jean-Marie Degryse

1 September 2014 | OTHER

Ma rk &kb The short-te prognostic value of forced expiratory volume in 1 second divided by height cubed (FENT.Ht-3) in a prospective cohort of people 8o years and older

Auteurs: Eralda Turkeshi, Bert Vaes, Elena Andreeva, Catharina Mathei, Wim Adriaensen, Gus Van Pottelbergh, and Jan Degryse

5 August 2014 | OTHER

Minimal Intensity Physical Activity (Standing and Walking) of Longer Duration Improves Insulin Action and Plasma Lipids More than Shorter Periods of Moderate to Vigorous Exercise (Cycling) in Sedentary Subjects When Energy Expenditure Is Comparable (vol 8, e55542, 2013)

Auteurs: BMFM Duvivier, NC Schaper, MA Bremers, G van Crombrugge, and PPCA Menheere

2 July 2014 | DISSERTATION

The quest for osmotic stress markers in Musa: From protein to gene and back in a non-model crop

Bananas and plantains are a major staple food and export product in more than 120 countries with a worldwide production of over 135 million tonnes per year. The Laboratory of Tropical Crop Improvement hosts the Bioversity International Musa Germpl...

Auteurs: Anne-Catherine Vanhove

1 July 2014 | ARTICLE

New advances in CMV and immunosenescence

Immunosenescence, defined as the age-associated dysregulation and dysfunction of the immune system, is characterized by impaired protective immunity and decreased efficacy of vaccines. An increasing number of immunological, clinical and epidemiolo...

Auteurs: Paolo Sansoni, Rosanna Vescovini, Francesco F Fagnoni, Arne Akbar, Ramon Arens, Yen-Ling Chiu, Luka Cičin-Šain, Julie Dechanet-Merville, Evelyna Derhovanessian, Sara Ferrando-Martinez, Claudio Franceschi, Daniela Frasca, Tamas Fulöp, David Furman, Effrossyni Gkrania-Klotsas, Felicia Goodrum, Beatrix Grubeck-Loebenstein, Mikko Hurme, Florian Kern, Daniele Lilleri, Miguel López-Botet, Andrea B Maier, Thomas Marandu, Arnaud Marchant, Cathy Matheï, Paul Moss, Aura Muntasell, Ester BM Remmerswaal, Natalie E Riddell, Kathrin Rothe, Delphine Sauce, Eui-Cheol Shin, Amanda M Simanek, Megan J Smithey, Cecilia Söderberg-Nauclér, Rafael Solana, Paul G Thomas, Rene van Lier, Graham Pawelec, and Janko Nikolich-Zugich

1 July 2014 | ARTICLE

Heritability and genetic etiology of habitual physical activity: a twin study with objective measures

Twin studies with objective measurements suggest habitual physical activity (HPA) are modestly to highly heritable, depending on age. We aimed to confirm or refute this finding and identify relevant genetic variants using a candidate gene approach...

Auteurs: M Gielen, MS Westerterp-Plantenga, FG Bouwman, AMCP Joosen, Robert Vlietinck, Cathérine Derom, MP Zeegers, ECM Mariman, and KR Westerterp

1 July 2014 | ARTICLE

Physical and mental quality of life in adult patients with haemophilia in Belgium: the impact of financial issues

In Belgium, where haemophilia affects approximately 1:7000 people (2011), data on patients' quality of life (QoL) is scarce. This project aims to assess physical and mental QoL (P-QoL and M-QoL) simultaneously, and to analyse the influence of diff...

Auteurs: AM Carvalhosa, S Henrard, C Lambert, and C Hermans

1 July 2014 | ARTICLE

Serious infections at a paediatric A&E

The most important way to reduce childhood mortality and morbidity is an early recognition of severe infections. The observed incidence of severe infections in Flanders is related to the clinical setting and is probably the highest in the pediatri...

Auteurs: Ine Hoogwijs, Jan Verbakel, Bert Aertgeerts, Dominique Bullens, and Frank Buntinx

16 June 2014 | DISSERTATION

Spiritualiteit aan het levenseinde: kunst of wetenschap?

Background: The World Health Organization defines palliativecare as encompassing the control of pain and other symptoms and psychological, social, and spiritual care. Most patients experiencing life-threatening illness want the medical team to ad...

Auteurs: Mieke Vermandere

6 June 2014 | ARTICLE

The Intego database: background, methods and basic results of a Flemish general practice-based continuous morbidity registration project

BACKGROUND: Intego is the only operational computerized morbidity registration network in Belgium based on general practice data. Intego collects data from over 90 general practitioners. All the information is routinely collected in the electro...

Auteurs: Carla Truyers, Geert Goderis, Harrie Dewitte, Marjan vanden Akker, and Frank Buntinx

4 June 2014 | ARTICLE

A patient-centered network approach to multidisciplinary-guideline development: a process evaluation

BACKGROUND: Guideline development and uptake are still suboptimal; they focus on clinical aspects of diseases rather than on improving the integration of care. We used a patient-centered network approach to develop five harmonized guidelines (one ...

Auteurs: Elvira ME Den Breejen, Mirrian AHW Hilbink, Willianne LDM Nelen, Tjerk J Wiersma, Jako S Burgers, Jan AM Kremer, and Rosella PMG Hermens

1 June 2014 | ARTICLE

Re: Defining Progression in Nonmuscle Invasive Bladder Cancer: It is Time for a New, Standard Definition

Auteurs: RT Bryan, KK Cheng, ND James, MP Zeegers, and DMA Wallace

1 June 2014 | ARTICLE

Langetermijnevolutie van de nierfunctie bij patiënten met type 2 diabetes

Auteurs: Geert Goderis, Gijs Van Pottelbergh, Carla Truyers, Viviane Van Calsteren, Etienne De Clercq, Carine Van Den Broeke, and Frank Buntinx

1 June 2014 | ARTICLE

'Dokter, moet ik nu wel of niet naar mijn borsten laten kijken?' - Bespreking van het KCE-rapport nr. 216

Auteurs: Marc Van Nuland

1 June 2014 | ARTICLE

Research into practice: acutely ill children

Auteurs: Ann Van den Bruel and Matthew Thompson

1 June 2014 | ARTICLE

Quality of antibiotic prescription during office hours and out-of-hours in Flemish primary care, using European quality indicators

BACKGROUND: European disease-specific antibiotic prescribing quality indicators (APQI) were proposed for seven acute indications (bronchitis, upper respiratory infection, cystitis, tonsillitis, sinusitis, otitis media and pneumonia): (a) the pe...

Auteurs: Niels Adriaenssens, Stefaan Bartholomeeusen, Philippe Ryckebosch, and Samuel Coenen

1 June 2014 | ARTICLE

Reply: Recurrent miscarriage: guidelines could be improved

Auteurs: E van den Boogaard, RPMG Hermens, JAM Kremer, F van der Veen, and M Goddijn

1 June 2014 | ARTICLE

Muscle Strength and Physical Performance as Predictors of Mortality, Hospitalization, and Disability in the Oldest Old

To evaluate the predictive value of muscle strength and physical performance in the oldest old for all-cause mortality; hospitalization; and the onset of disability, defined as a decline in activities of daily living (ADLs), independent of muscle ...

Auteurs: Delphine Legrand, Bert Vaes, Cathy Matheï, Wim Adriaensen, Gijs Van Pottelbergh, and Jean-Marie Degryse

1 June 2014 | ARTICLE

Predicting successful intended vaginal delivery after previous caesarean section: external validation of two predictive models in a Dutch nationwide registration-based cohort with a high intended vaginal delivery rate

OBJECTIVE: To externally validate two models from the USA (entry-to-care [ETC] and close-to-delivery [CTD]) that predict successful intended vaginal birth after caesarean (VBAC) for the Dutch population. DESIGN: A nationwide registration-based coh...

Auteurs: ENC Schoorel, S Melman, SMJ van Kuijk, WA Grobman, A Kwee, BWJ Mol, JG Nijhuis, LJM Smits, R Aardenburg, K de Boer, FMC Delemarre, IM van Dooren, MTM Franssen, G Kleiverda, M Kaplan, SMI Kuppens, FTH Lim, JM Sikkema, E Smid-Koopman, H Visser, FPJM Vrouenraets, M Woiski, RPMG Hermens, and HCJ Scheepers

1 June 2014 | ARTICLE

Sepsis and meningitis in hospitalized children: performance of clinical signs and their prediction rules in a case-control study

Feverish illness is a common presentation to acute pediatric services. Clinical staff faces the challenge of differentiating the few children with meningitis or sepsis from the majority with self-limiting illness. We aimed to determine the diagnos...

Auteurs: Jan Verbakel, Roderick MacFaul, Bert Aertgeerts, Frank Buntinx, and Matthew Thompson

1 May 2014 | ARTICLE

Point-of-care prognosis for common musculoskeletal pain in older adults

Auteurs: Jan Verbakel

1 May 2014 | ARTICLE

Association between recent herpes zoster but not herpes simplex infection and subsequent risk of malignancy in women: a retrospective cohort study

SUMMARY The association between herpes zoster and subsequent cancer risk is still unclear. Consequently, doubts remain regarding the need for investigation of herpes patients for co-existing or subsequent malignancy. This is a retrospective coh...

Auteurs: Frank Buntinx, S Bartholomeeusen, Ann Belmans, C Mathei, Ghislain Opdenakker, K Sweldens, Carla Truyers, and Marc Van Ranst

1 May 2014 | OTHER

Association between recent herpes zoster but not herpes simplex infection and subsequent risk of malignancy in women: a retrospective cohort study - CORRIGENDUM

Auteurs: F Buntinx, S Bartholomeeusen, A Belmans, C Mathei, G Opdenakker, K Sweldens, C Truyers, and M Van Ranst

1 May 2014 | ARTICLE

Een ruimer perspectief op somberheid in de palliatieve fase

Dat patiënten in de palliatieve fase somebr eb verdrietig zijn, is normaal en begrijpelijk. De exclusief psychiatrrische blik die zulke somebrheid benoemt asl 'depressieve stoornis', is in zo'n situatie verraderlijk. Zij kan beter verruild worden ...

Auteurs: Franca Warmenhoven, Mieke Vermandere, Peter Lucassen, Kris Vissers, Bert Aertgeerts, and Jan De Lepeleire

1 May 2014 | OTHER

The associationof common variants in PCSK1 with obesity: A Meta-analysis

Auteurs: Pieter Stijnen, Krizia Tuand, Bert Aertgeerts, and John Creemers

23 April 2014 | DISSERTATION

Sarcopenia in very old persons. A study of the relationship between muscle mass, muscle strength, physical performance and adverse events

Auteurs: Delphine Legrand

9 April 2014 | ARTICLE

The effectiveness of a semi-tailored facilitator-based intervention to optimise chronic care management in general practice: a stepped-wedge randomised controlled trial

BACKGROUND: The Danish health care sector is reorganising based on disease management programmes designed to secure integrated and high quality chronic care across hospitals, general practitioners and municipalities. The disease management program...

Auteurs: Tina Drud Due, Thorkil Thorsen, Marius Brostrom Kousgaard, Volkert Dirk Siersma, and Frans Boch Waldorff

1 April 2014 | ARTICLE

Reduction of Potentially Inappropriate Medications Using the STOPP Criteria in Frail Older Inpatients: A Randomised Controlled Study

Hospital admissions may provide an opportunity to discontinue potentially inappropriate medications (PIMs) in older patients. Little is known about the effect of using the Screening Tool of Older People's potentially inappropriate Prescriptions (S...

Auteurs: O Dalleur, B Boland, C Losseau, S Henrard, D Wouters, N Speybroeck, Jean-Marie Degryse, and A Spinewine

27 March 2014 | ARTICLE

Protocol for a randomized comparison of integrated versus consecutive dual task practice in Parkinson's disease: the DUALITY trial

BACKGROUND: Multiple tasking is an integral part of daily mobility. Patients with Parkinson's disease have dual tasking difficulties due to their combined motor and cognitive deficits. Two contrasting physiotherapy interventions have been proposed...

Auteurs: Carolien Strouwen, Esther ALM Molenaar, Samyra HJ Keus, Liesbeth Munks, Marten Munneke, Wim Vandenberghe, Bastiaan R Bloem, and Alice Nieuwboer