Publicaties

BACKGROUND: Exercise stress testing offers a non-invasive, less expensive way of risk stratification prior to coronary angiography, and a negative stress test may actually avoid angiography. However, previous meta-analyses have not included all ex...

There is an urgent need for potent inhibitors of dengue virus (DENV) replication for the treatment and/or prophylaxis of infections with this virus. We here report on an aglycon analogue of the antibiotic teicoplanin (code name LCTA-949) that inhi...

RATIONALE, AIMS AND OBJECTIVES: Adverse events are unintended patient injuries or complications that arise from health care management resulting in death, disability or prolonged hospital stay. Adverse events that require critical care are a consi...

Increased body mass index (BMI) is a worldwide health issue. Individual differences in the susceptibility to increased BMI could be related to genes or environment. We performed a systematic review of genetic studies on BMI in pre-adolescence, you...

BACKGROUND: For preventive interventions in general practice to succeed, patients' points of view must be taken into account in addition to those of GPs. OBJECTIVE: To explore patients' views and beliefs about the importance of lifestyle and preve...

To evaluate the effect of inpatient geriatric consultation teams (IGCTs), which have been introduced to improve the quality of care of older persons hospitalized on nongeriatric wards, on delirium and overall cognitive functioning in older adults ...

Background: In Belgium, bladder cancer is the fifth most common cancer in males (5.2%) and the sixth mostfrequent cause of death from cancer in males (3.8%). Previous epidemiological studies have consistently reportedthat selenium concentrations w...

Pernicious anemia is a chronic disease, leading to a decreased absorption of vitamin B12, caused by the lack of intrinsic factor in gastric juice. It is mainly an autoimmune disease, characterized by the occurrence of antibodies directed against p...

IntroductionTheoretically, doing what has been proven to be effective or stopping was is not working has the potential to provide health benefits or to reduce patient risks and waste of health care resources. As a consequence, it is essential that...

BACKGROUND: chronic kidney disease (CKD) is a pathology for which the prevalence increases with age but it remains uncertain whether this is due to ageing. METHODS: all patients at least 50 years old with at least two creatinine measurements in ...

Although the vast majority of children with acute infections are managed at home, this is one of the most common problems encountered in children attending emergency departments (EDs) and primary care. Distinguishing children with serious infectio...

The purpose of this dissertation is to gain insights into evidence-based communication skills training in general practice vocational training.The Introductory Chapter provides arguments to explain why this topic is worth investigating and highli...

OBJECTIVES: In addition to diagnosing the disease, establishing the care needs of people suffering from dementia is of paramount importance. Based on a literature review and expert advice, a working document has been drawn up in this article to de...

BACKGROUND: Little is known about the relationship between cardiac dysfunction and poor functioning in the elderly. This study sought to describe the prevalence of cardiac dysfunction in the very elderly and to investigate the correlation between ...

Care diagnosis for demented patients living at home. A new concept? Objectives: In addition to diagnosing the disease, establishing the care needs of people suffering from dementia is of paramount importance. Based on a literature review and exper...

OBJECTIVES: To estimate the heritabilities of maximally attained lung function in young adult twins, and to examine whether circulating leptin, leptin (LEP) and leptin receptor (LEPR) gene polymorphisms are associated with maximally attained lung ...

CONTEXT: The long-term mortality in adults treated with recombinant GH during childhood has been poorly investigated. Recently released data from the French part of the European Union Safety and Appropriateness of GH treatments in Europe (EU SAGhE...